Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions Review


Authors: DeVirgiliis, L.; Goode, N. J.; McDowell, K. W.; English, K. L.; Novo, R.; Botros, V.; Agwu, G.; Scott, J. M.; Ploutz-Snyder, L. L.
Review Title: Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions
Abstract: Long-duration spaceflight impacts essentially every system in the human body, resulting in multisystem deconditioning that might impair the health and performance of crewmembers, particularly on long-duration exploration missions to Mars. In this review, we apply the sport science model of athlete monitoring, testing and training to astronauts; tactical athletes, whose occupation includes physically demanding tasks. We discuss exploration-specific physiological monitoring modalities and provide a brief historical overview of physiological countermeasures to spaceflight. Finally, we suggest countermeasures to protect exploration crew health and performance, including targeted preflight and in-flight exercise training, in-flight exercise hardware and adjunct individualized nutrition and sleep considerations. Mars exploration missions will be exemplars of the astronaut–athlete paradigm. An integrated approach to physiological monitoring and countermeasures will maximize the likelihood of exploration mission success. © 2025 The Author(s). Experimental Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.
Keywords: review; exercise; physiology; training; etiology; sleep; duration; exercise physiology; sport; athlete; cosmonaut; space flight; physiologic monitoring; human; deconditioning; spaceflight; crew member; countermeasures; athlete monitoring; human/environmental and exercise physiology; sport science; astronomy
Journal Title: Experimental Physiology
ISSN: 0958-0670
Publisher: Wiley Blackwell  
Publication status: Online ahead of print
Date Published: 2025-04-08
Online Publication Date: 2025-04-08
Language: English
DOI: 10.1113/ep091595
PROVIDER: scopus
PUBMED: 40198226
DOI/URL:
Notes: Review -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- Source: Scopus
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MSK Authors
  1. Jessica M Scott
    73 Scott
  2. Robert Novo
    5 Novo