Advancements in artificial intelligence for prostate cancer: Optimizing diagnosis, treatment, and prognostic assessment Review


Authors: Arita, Y.; Roest, C.; Kwee, T. C.; Paudyal, R.; Lema-Dopico, A.; Fransen, S.; Hirahara, D.; Takaya, E.; Ueda, R.; Ruby, L.; Nissan, N.; Schwartz, L. H.; Shukla-Dave, A.; Akin, O.
Review Title: Advancements in artificial intelligence for prostate cancer: Optimizing diagnosis, treatment, and prognostic assessment
Abstract: Objective: This review provides a comprehensive overview of the current research landscape on artificial intelligence (AI) in prostate cancer (PCa) management, highlighting its potential to enhance diagnosis, improve medical image quality, facilitate risk stratification, and aid prognosis. The review also identifies opportunities and challenges associated with integrating AI into clinical practice. Methods: This review synthesizes findings from recent studies on AI applications in PCa management. It examines the use of machine learning and deep learning techniques in diagnostic imaging, surgical skill assessment, and outcome prediction. The analysis emphasizes empirical evidence demonstrating the efficacy and limitations of AI models in clinical settings. Results: AI, particularly machine learning and deep learning algorithms, is improving diagnostic accuracy by analyzing medical images with greater efficiency and precision compared to traditional methods. AI-based tools are also being developed for surgical skill assessment, offering objective evaluations and feedback to surgeons. Additionally, AI applications in predicting patient outcomes are facilitating the creation of personalized treatment plans. Empirical evidence shows that AI models exhibit higher sensitivity and specificity in detecting clinically significant PCa, outperforming conventional diagnostic techniques. Conclusion: AI holds significant promise for transforming PCa management by improving diagnostic accuracy, personalizing treatment plans, and enhancing patient outcomes. While the evidence underscores its potential, challenges such as the need for larger, more diverse datasets and addressing implementation barriers remain critical. Despite these hurdles, the benefits of AI in PCa management represent a compelling area for future research and clinical integration. © 2025 Editorial Office of Asian Journal of Urology
Keywords: pathology; prostate cancer; artificial intelligence; mri; computed tomography; machine learning; deep learning; radiomics
Journal Title: Asian Journal of Urology
ISSN: 2214-3882
Publisher: The Second Military Medical University  
Publication status: Online ahead of print
Date Published: 2025-02-21
Online Publication Date: 2025-02-21
Language: English
DOI: 10.1016/j.ajur.2024.12.001
PROVIDER: scopus
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF. Corresponding MSK author is Oguz Akin -- Source: Scopus
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MSK Authors
  1. Lawrence H Schwartz
    313 Schwartz
  2. Amita Dave
    141 Dave
  3. Oguz Akin
    273 Akin
  4. Ramesh Paudyal
    40 Paudyal
  5. Yuki Arita
    22 Arita
  6. Noam Nissan
    12 Nissan
  7. Lisa Ruby
    9 Ruby