Aging-related, senescence-associated secretory phenotype and allogeneic hematopoietic cell transplantation outcomes in older patients Research Letter


Authors: Jeng, M. Y.; Wong, P.; Flynn, J. R.; Ritter, E.; Ho, C.; Ruiz, J. D.; Jakubowski, A. A.; Papadopoulos, E. B.; Shaffer, B. C.; Ponce, D. R.; Tamari, R.; Young, J. W.; Angel-Perales, M.; Devlin, S.; Giralt, S. A.; Lin, R. J.
Title: Aging-related, senescence-associated secretory phenotype and allogeneic hematopoietic cell transplantation outcomes in older patients
Keywords: adult; controlled study; treatment outcome; aged; major clinical study; overall survival; mortality; cancer recurrence; c reactive protein; interleukin 2; progression free survival; interleukin 10; interleukin 12p70; interleukin 13; interleukin 1beta; interleukin 4; interleukin 8; cohort analysis; acute lymphoblastic leukemia; age; acute graft versus host disease; myeloablative conditioning; myelodysplastic syndrome; feasibility study; karnofsky performance status; gamma interferon; quantitative analysis; graft versus host reaction; interleukin 6; allogeneic hematopoietic stem cell transplantation; aging; senescence; calcineurin inhibitor; myeloproliferative neoplasm; correlational study; tumor necrosis factor; cumulative incidence; allogeneic transplant; acute myeloid leukemia; myeloid malignancies; geriatric oncology; sasp; non relapse mortality; senescence-associated secretory phenotype; human; article; aging biomarkers; disease risk assessment
Journal Title: Journal of Geriatric Oncology
Volume: 16
Issue: 8
ISSN: 1879-4068
Publisher: Elsevier Inc.  
Date Published: 2025-11-01
Start Page: 102346
Language: English
DOI: 10.1016/j.jgo.2025.102346
PROVIDER: scopus
PMCID: PMC12380173
PUBMED: 40834739
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Richard J. Lin -- Source: Scopus
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MSK Authors
  1. Sergio Andres Giralt
    1070 Giralt
  2. Phillip Wong
    82 Wong
  3. Miguel-Angel Perales
    943 Perales
  4. James W Young
    320 Young
  5. Erika Ritter
    38 Ritter
  6. Sean McCarthy Devlin
    616 Devlin
  7. Roni Tamari
    214 Tamari
  8. Brian Carl Shaffer
    176 Shaffer
  9. Richard Jirui Lin
    132 Lin
  10. Jessica Flynn
    183 Flynn
  11. Josel Dumo Ruiz
    55 Ruiz
  12. Mark Yungjie Jeng
    7 Jeng