Rethinking local therapy for rectal cancer in the era of precision oncology - When less is more Editorial


Authors: Bercz, A.; Bauer, P. S.; Smith, J. J.
Title: Rethinking local therapy for rectal cancer in the era of precision oncology - When less is more
Keywords: excision; cancer recurrence; patient selection; note; cancer staging; nuclear magnetic resonance imaging; antineoplastic agent; quality of life; local therapy; neoadjuvant chemotherapy; rectum cancer; chemoradiotherapy; observation; recurrence free survival; total mesorectal excision; pathological complete response; randomized controlled trial (topic); transanal endoscopic microsurgery; consolidation chemotherapy; human; circulating tumor dna; personalized cancer therapy; therapy escalation
Journal Title: JAMA Surgery
Volume: 160
Issue: 7
ISSN: 2168-6254
Publisher: American Medical Association  
Date Published: 2025-07-01
Start Page: 793
End Page: 794
Language: English
DOI: 10.1001/jamasurg.2025.1377
PUBMED: 40434795
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Jesse Joshua Smith
    231 Smith
  2. Aron Peter Bercz
    15 Bercz
  3. Philip S. Bauer
    3 Bauer