Bronchoesophageal–spinal fistula development in a patient with thyroid cancer Journal Article


Authors: Zhu, A.; Chen, L. L.; Tao, J.
Article Title: Bronchoesophageal–spinal fistula development in a patient with thyroid cancer
Abstract: Concurrent bronchoesophageal fistulas (BEF) and spinal–esophageal fistulas (SEF) are exceedingly rare complications of esophageal perforation, particularly in cancer patients undergoing multimodal therapies. This report describes a patient with metastatic papillary thyroid cancer who developed BEF and SEF following thyroidectomy, radiotherapy, and systemic antineoplastic therapies. Despite multiple interventions, including esophageal stenting, nutritional support, and antifungal therapy, the patient’s condition deteriorated due to recurrent infections and progressive organ dysfunction. This case highlights the complex interplay between oncologic treatments and their complications, underscoring the need for early recognition, multidisciplinary management, and novel therapeutic strategies for high-risk patients. © 2025 Wolters Kluwer Health. All rights reserved.
Keywords: intensive care; thyroid cancer; tracheostomy; critical care; respiratory failure
Journal Title: Journal of the American Association of Nurse Practitioners
ISSN: 2327-6886
Publisher: American Association of Nurse Practitioners  
Publication status: Online ahead of print
Date Published: 2025-07-08
Online Publication Date: 2025-07-08
Language: English
DOI: 10.1097/jxx.0000000000001166
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Leon Lin Chen
    53 Chen
  2. Jing Tao
    4 Tao
  3. Andrew Zhu
    3 Zhu