The impact of psychiatric diagnosis on patient reported outcomes in breast-conserving surgery patients Journal Article
| Authors: | Gabay, A. J.; Wang, J.; Boe, L. A.; Stern, C. S.; Mehrara, B.; Moo, T. A.; Nelson, J. A.; Tadros, A. |
| Article Title: | The impact of psychiatric diagnosis on patient reported outcomes in breast-conserving surgery patients |
| Abstract: | Background: Psychiatric conditions are known to impact outcomes in breast reconstruction patients, but their effect on patient-reported outcomes in breast-conserving surgery (BCS) patients remains unclear. This study investigates how psychiatric diagnoses—both preexisting and post-cancer—affect BREAST-Q scores in BCS patients. Methods: We conducted a retrospective review of patients who underwent BCS from 2017–2022 at Memorial Sloan Kettering, examining BREAST-Q scores collected in routine care preoperatively and annually for 3 years postoperatively. Patients were categorized as having no psychiatric diagnosis, a diagnosis before breast cancer, or a diagnosis after. Kruskal-Wallis and Wilcoxon tests compared scores, and multivariable linear mixed effects models adjusted for confounders. Results: Of 7937 patients, 273 were diagnosed before breast cancer, 2971 were diagnosed after, and 4693 had no history of psychiatric diagnosis. Among those with a psychiatric diagnosis, 81% had anxiety. Compared with patients without psychiatric diagnoses, those with diagnoses—pre- or post-cancer—reported significantly lower scores in Satisfaction with Breasts, Sexual Well-Being, and Psychosocial Well-Being (p < 0.001). No significant difference was observed in Physical Well-Being scores for precancer diagnoses (p = 0.4) compared with patients without psychiatric diagnoses. Precancer diagnoses were associated with more pronounced declines across most domains compared to postcancer diagnoses. Conclusions: Psychiatric diagnoses are associated with lower BREAST-Q scores after BCS, especially when diagnosed before cancer. These findings emphasize the importance of integrated mental health support in optimizing quality of life for breast cancer patients. © Society of Surgical Oncology 2025. |
| Keywords: | breast cancer; lumpectomy; breast conserving surgery; patient reported outcomes; breast-q; psychiatric disorder |
| Journal Title: | Annals of Surgical Oncology |
| ISSN: | 1068-9265 |
| Publisher: | Springer |
| Publication status: | Online ahead of print |
| Date Published: | 2025-07-12 |
| Online Publication Date: | 2025-07-12 |
| Language: | English |
| DOI: | 10.1245/s10434-025-17782-z |
| PROVIDER: | scopus |
| PUBMED: | 40652151 |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Audree Tadros -- Source: Scopus |
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