Teriparatide as an adjuvant therapy in the management of advanced-stage medication-related osteonecrosis of the jaw Journal Article


Authors: Singh, A.; Chung, K.; Huryn, J. M.; Estilo, C. L.; Farooki, A.; Yom, S. K.
Article Title: Teriparatide as an adjuvant therapy in the management of advanced-stage medication-related osteonecrosis of the jaw
Abstract: Teriparatide, recombinant human parathyroid hormone, is a US Food and Drug Administration (FDA)-approved drug used for the treatment of osteoporosis in men and postmenopausal women. Recent studies have shown that it may promote bone healing in medication-related osteonecrosis of the jaw (MRONJ). We describe a case of successful management of advanced-stage MRONJ with teriparatide therapy that was initially prescribed for osteoporosis. This case demonstrates that in patients with progressive MRONJ with significant pain and frequent flares of acute infection, teriparatide may be a viable adjunct in treating MRONJ, as well as helping alleviate symptoms and improve quality of life. (Oral Surg Oral Med Oral Pathol Oral Radiol YEAR;VOL:page range) © 2025
Journal Title: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
ISSN: 2212-4403
Publisher: Elsevier B.V.  
Publication status: Online ahead of print
Date Published: 2025-04-10
Online Publication Date: 2025-04-10
Language: English
DOI: 10.1016/j.oooo.2025.04.001
PROVIDER: scopus
PUBMED: 40399210
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF. Corresponding MSK author is SaeHee K. Yom -- Source: Scopus
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MSK Authors
  1. Azeez Farooki
    77 Farooki
  2. Joseph M Huryn
    109 Huryn
  3. Cherry Estilo
    94 Estilo
  4. SaeHee Kim Yom
    43 Yom
  5. Annu Singh
    23 Singh
  6. Kevin Chung
    3 Chung