Authors: | Ruan, T.; Keshari, K. R. |
Review Title: | Imaging tumor metabolism |
Abstract: | Molecular imaging-the mapping of molecular and cellular processes in vivo-has the unique capability to interrogate cancer metabolism in its spatial contexts. This work describes the usage of the two most developed modalities for imaging metabolism in vivo: positron emission tomography (PET) and magnetic resonance (MR). These techniques can be used to probe glycolysis, glutamine metabolism, anabolic metabolism, redox state, hypoxia, and extracellular acidification. This review aims to provide an overview of the strengths and limitations of currently available molecular imaging strategies. Copyright © 2025 Cold Spring Harbor Laboratory Press; all rights reserved. |
Keywords: | nuclear magnetic resonance imaging; positron emission tomography; magnetic resonance imaging; neoplasm; neoplasms; metabolism; molecular imaging; diagnostic imaging; positron-emission tomography; glycolysis; glutamine; procedures; humans; human |
Journal Title: | Cold Spring Harbor Perspectives in Medicine |
Volume: | 15 |
Issue: | 6 |
ISSN: | 2157-1422 |
Publisher: | Cold Spring Harbor Laboratory Press |
Date Published: | 2025-06-01 |
Start Page: | a041551 |
Language: | English |
DOI: | 10.1101/cshperspect.a041551 |
PUBMED: | 39009443 |
PROVIDER: | scopus |
PMCID: | PMC12128880 |
DOI/URL: | |
Notes: | Review -- MSK corresponding author is Kayvan Rahimi-Keshari, listed on the original puoblication as "Kayvan R. Keshari" -- Source: Scopus |