Imaging tumor metabolism Review


Authors: Ruan, T.; Keshari, K. R.
Review Title: Imaging tumor metabolism
Abstract: Molecular imaging-the mapping of molecular and cellular processes in vivo-has the unique capability to interrogate cancer metabolism in its spatial contexts. This work describes the usage of the two most developed modalities for imaging metabolism in vivo: positron emission tomography (PET) and magnetic resonance (MR). These techniques can be used to probe glycolysis, glutamine metabolism, anabolic metabolism, redox state, hypoxia, and extracellular acidification. This review aims to provide an overview of the strengths and limitations of currently available molecular imaging strategies. Copyright © 2025 Cold Spring Harbor Laboratory Press; all rights reserved.
Keywords: nuclear magnetic resonance imaging; positron emission tomography; magnetic resonance imaging; neoplasm; neoplasms; metabolism; molecular imaging; diagnostic imaging; positron-emission tomography; glycolysis; glutamine; procedures; humans; human
Journal Title: Cold Spring Harbor Perspectives in Medicine
Volume: 15
Issue: 6
ISSN: 2157-1422
Publisher: Cold Spring Harbor Laboratory Press  
Date Published: 2025-06-01
Start Page: a041551
Language: English
DOI: 10.1101/cshperspect.a041551
PUBMED: 39009443
PROVIDER: scopus
PMCID: PMC12128880
DOI/URL:
Notes: Review -- MSK corresponding author is Kayvan Rahimi-Keshari, listed on the original puoblication as "Kayvan R. Keshari" -- Source: Scopus
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MSK Authors
  1. Thomas Lipa Ruan
    4 Ruan