Chronic myeloid neoplasms Book Section
| Authors: | Arcila, M. E.; Ho, C. |
| Editors: | Tafe, L. J.; Arcila, M. E. |
| Article/Chapter Title: | Chronic myeloid neoplasms |
| Abstract: | Chronic myeloid neoplasms are group of clinically heterogenous diseases characterized by a wide range of abnormalities affecting the function of cells in the myeloid lineage. Their classification is based on an integrated, multimodality approach that requires the strict correlation of clinical, morphologic, and genetic features. Cytogenetic and molecular genetic studies are an essential component of the assessment of these patients at the time of diagnosis and in the monitoring phase to assess disease progression and for risk stratification across the disease spectra. In this chapter, we highlight the most common somatic genetic abnormalities identified in this group of diseases. © Springer Nature Switzerland AG 2020. |
| Keywords: | molecular genetics; disease progression; risk stratification; multi-modality; genetic abnormality; genetic studies; morpho-logics; disease spectrum |
| Book Title: | Genomic Medicine: A Practical Guide |
| ISBN: | 978-3-030-22921-4 |
| Publisher: | Springer |
| Publication Place: | Cham, Switzerland |
| Date Published: | 2020-01-01 |
| Start Page: | 235 |
| End Page: | 251 |
| Language: | English |
| DOI: | 10.1007/978-3-030-22922-1_15 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book chapter: 15 -- Source: Scopus |
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