Novel dual gene fusions identified in a late pulmonary metastasis of an infantile fibrosarcoma-like tumor Journal Article
| Authors: | Schoedel, K.; Hegazy, S.; Zilla, M. L.; Chang, J.; Nacev, B. A. |
| Article Title: | Novel dual gene fusions identified in a late pulmonary metastasis of an infantile fibrosarcoma-like tumor |
| Abstract: | The list of potential gene fusions involving sarcomas, and particularly infantile fibrosarcoma-like tumors, continues to expand. The receptor tyrosine kinases are dysregulated in several tumor types, underscoring their roles in neoplasia. In this case presentation, we describe a pulmonary metastasis with two novel gene fusions (FKBP5::PRKCA and in-frame SEPT7::RAF1) occurring at least two decades after the primary tumor developed. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024. |
| Keywords: | gene fusion; next generation sequencing; infantile fibrosarcoma |
| Journal Title: | Virchows Archiv |
| Volume: | 486 |
| Issue: | 5 |
| ISSN: | 0945-6317 |
| Publisher: | Springer |
| Date Published: | 2025-05-01 |
| Start Page: | 1069 |
| End Page: | 1072 |
| Language: | English |
| DOI: | 10.1007/s00428-024-03882-w |
| PUBMED: | 39078429 |
| PROVIDER: | scopus |
| PMCID: | PMC11779980 |
| DOI/URL: | |
| Notes: | Erratum issued, see DOI: 10.1007/s00428-024-03990-7 -- Source: Scopus |
