Towards opioid access without excess Review


Authors: Rosa, W. E.; Knaul, F. M.; Touchton, M.; Bhadelia, A.; Humphreys, K.; Radbruch, L.; Rajagopal, M. R.
Review Title: Towards opioid access without excess
Abstract: A decade after World Health Assembly Resolution 67.19 recognised palliative care as a component of comprehensive care and universal health coverage throughout the life course, a balanced approach to opioid access remains elusive. Disparities in the alleviation of serious health-related suffering persist, characterised by two parallel opioid-related public health crises: a pandemic of unrelieved pain and an opioid addiction epidemic. The pain pandemic is largely driven by the opioid access abyss and primarily affects over 50 million people with serious health-related suffering living in low-income and middle-income countries. Conversely, several high-income countries have been affected by an opioid addiction epidemic. An estimated 39·5 million people struggle with opioid use disorder worldwide, the vast majority living in North America. In this Viewpoint, we describe these parallel crises, argue for pain relief as a global public good, and identify stewardship roles of WHO member states and local actors to use a balanced approach in galvanising the global health system to simultaneously close the global pain divide and move towards opioid access without excess in alignment with Sustainable Development Goal targets focused on the prevention of substance abuse (3.5) and universal health coverage (3.8). © 2025 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
Keywords: review; pain; opiate; palliative therapy; narcotic analgesic agent; world health organization; analgesics, opioid; opioid-related disorders; epidemiology; drug therapy; analgesia; therapy; health care access; north america; prevention and control; epidemic; substance abuse; prevention; global health; lowest income group; health services accessibility; pandemic; humans; human; middle income country; high income country; opioid epidemic; opioid use disorder; open access publishing; sustainable development goal; universal health insurance; opioid-related disorder
Journal Title: The Lancet Public Health
Volume: 10
Issue: 5
ISSN: 2468-2667
Publisher: Elsevier Inc.  
Date Published: 2025-05-01
Start Page: e422
End Page: e427
Language: English
DOI: 10.1016/s2468-2667(25)00035-0
PUBMED: 40023173
PROVIDER: scopus
PMCID: PMC12145491
DOI/URL:
Notes: Review -- MSK corresponding author is William Rosa -- Source: Scopus
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  1. William   Rosa
    206 Rosa