Updates to Microhematuria: AUA/SUFU Guideline (2025) Journal Article


Authors: Barocas, D. A.; Lotan, Y.; Matulewicz, R. S.; Raman, J. D.; Westerman, M. E.; Kirkby, E.; Pak, L. J.; Souter, L.
Article Title: Updates to Microhematuria: AUA/SUFU Guideline (2025)
Abstract: Purpose:In 2023 the AUA in collaboration with the Society for Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) requested an Update Literature Review to incorporate new evidence generated since the 2020 publication of this Guideline. The resulting 2025 Microhematuria Guideline Amendment addresses updated recommendations to provide a clinical framework for the diagnosis, evaluation, and follow-up of microhematuria.Materials and Methods:In 2024, this Guideline was reviewed via the AUA Update Literature Review process, which identified 82 studies for full-text review that were published between December 2019 and June 7, 2024. Of those 82 studies, 23 met inclusion criteria for qualitative synthesis. The subsequent amendment is based on data released since the initial 2020 publication of this Guideline.Results:The Panel developed evidence- and consensus-based statements based on an updated review to provide guidance on evaluation and management of microhematuria. These updates are detailed herein.Conclusions:This update provides several new insights, including a revised risk stratification system, updated information regarding use of urine-based tumor markers and cytology, and new guidance on diagnosis and surveillance. This Guideline will require further review as the diagnostic and treatment options in this space continue to evolve. © 2025 by AMERICAN UROLOGICAL ASSOCIATION EDUCATION AND RESEARCH, INC.
Keywords: anamnesis; follow up; computer assisted tomography; kidney disease; evidence based practice; smoking; creatinine; creatinine blood level; practice guideline; bladder cancer; tumor marker; renal cell carcinoma; hematuria; high risk patient; risk assessment; urothelium; societies, medical; family history; carcinoma in situ; diagnosis; echography; urology; urothelial carcinoma; medical society; consensus development; cystoscopy; physical examination; clinical practice guideline; urinalysis; transitional cell carcinoma; urography; lynch syndrome; therapy; blood pressure measurement; etiology; medical history; intermediate risk patient; micturition; urine cytology; clinician; low risk patient; gynecologic disease; bladder epithelium; humans; human; female; article; hereditary tumor syndrome; disease risk assessment; ct urogram; urine markers
Journal Title: Journal of Urology
Volume: 213
Issue: 5
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 2025-01-01
Start Page: 547
End Page: 557
Language: English
DOI: 10.1097/ju.0000000000004490
PUBMED: 40013563
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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