Osimertinib-chemotherapy synergy in EGFR-mutant NSCLC: Advancing central nervous system control amidst toxicity considerations Editorial


Authors: Kumar, R.; Miao, E.; Pike, L. R. G.
Title: Osimertinib-chemotherapy synergy in EGFR-mutant NSCLC: Advancing central nervous system control amidst toxicity considerations
Keywords: cancer chemotherapy; cancer survival; gene mutation; overall survival; drug potentiation; monotherapy; systemic therapy; note; antineoplastic agent; progression free survival; quality of life; morbidity; epidermal growth factor receptor; local therapy; cancer mortality; blood brain barrier; stereotactic radiosurgery; cancer control; combination therapy; adverse drug reaction; non small cell lung cancer; central nervous system metastasis; randomized controlled trial (topic); whole brain radiotherapy; phase 3 clinical trial (topic); brain tissue; patient-reported outcome; cancer prognosis; combination drug therapy; disease burden; human; symptom assessment; osimertinib; european organization for research and treatment of cancer quality of life questionnaire core 30; brain metastases (bms); central nervous system efficacy (cns efficacy); epidermal growth factor receptor-mutated non-small cell lung cancer (egfr-mutated nsclc)
Journal Title: Translational Cancer Research
Volume: 14
Issue: 4
ISSN: 2218-676X
Publisher: Pioneer Bioscience Publishing Company  
Date Published: 2025-04-30
Start Page: 2188
End Page: 2191
Language: English
DOI: 10.21037/tcr-2024-2207
PROVIDER: scopus
PMCID: PMC12079210
PUBMED: 40386260
DOI/URL:
Notes: Source: Scopus
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  1. Luke R. Pike
    63 Pike
  2. Emily A Miao
    8 Miao
  3. Rahul Kumar
    2 Kumar