Treatment patterns and clinical outcomes of patients with HER2-positive T1micN0 breast cancer: A single-center analysis Journal Article

   


Authors: Yeh, C.; Han, R.; Kulkarni, A.; White, C.; Chen, Y.; Hanna, M. G.; Brogi, E.; Seidman, A. D.
Article Title: Treatment patterns and clinical outcomes of patients with HER2-positive T1micN0 breast cancer: A single-center analysis
Abstract: We conducted a retrospective analysis of 213 patients with HER2+ T1micN0 breast cancer. Patients with ≥5 foci of microinvasion received more aggressive treatment with higher rates of sentinel lymph node biopsy and adjuvant chemotherapy/HER2-targeted therapy (CT/H2TT) than patients with 1–4 foci. We did not detect significant differences in invasive disease-free survival between patients with 1–4 and ≥5 foci, or between patients with ≥5 foci who did and did not receive adjuvant CT/H2TT. © The Author(s) 2025.
Journal Title: npj Breast Cancer
Volume: 11
ISSN: 2374-4677
Publisher: Nature Publishing Group  
Date Published: 2025-05-24
Start Page: 47
Language: English
DOI: 10.1038/s41523-025-00759-2
PROVIDER: scopus
PMCID: PMC12103504
PUBMED: 40413163
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-105005709218&doi=10.1038%2fs41523-025-00759-2&partnerID=40&md5=b7361633b36799ab10f45fa431dbfca6
Notes: Article -- MSK corresponding author is Andrew Seidman -- Source: Scopus
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MSK Authors
  1. Andrew D Seidman
    318 Seidman
  2. Edi Brogi
    515 Brogi
  3. Matthew George Hanna
    101 Hanna
  4. Yuan Chen
    38 Chen
  5. Charlie White
    40 White
  6. Celine Yeh
    6 Yeh
  7. Rachel Hae-Sung Han
    5 Han
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