Outcomes of palliative hemipelvectomy in comprehensive cancer center patients with metastatic cancer: Retrospective study Journal Article


Authors: Rosen, R.; Gulati, A.; Bartsch, C.; Santos, E. P.; Nash, G.; Omer, D.; Aysola, V.; Curry, M.; Vaynrub, M.
Article Title: Outcomes of palliative hemipelvectomy in comprehensive cancer center patients with metastatic cancer: Retrospective study
Abstract: BACKGROUND: Hemipelvectomy is a complex operation that is usually performed with curative intent. It is rarely performed for palliation in patients with advanced cancer, and its efficacy in achieving palliation is unknown. STUDY DESIGN: Retrospective review of 10 patients with stage IV cancer who underwent palliative hemipelvectomy at a comprehensive cancer center. RESULTS: Median age of the cohort was 60 years; 7 patients were male. Five patients had previous radiotherapy to the pelvic bone. Hemipelvectomies involved 1 to 2 Enneking-Dunham pelvic zones in 6 patients and 3 to 4 zones in 4 patients. Six patients had Clavien-Dindo complication of grade 3 or higher. Median overall survival was 6.6 months. Surgical complication resulted in death in 3 patients. At their 3-month follow-up, 5 of 8 living patients had increased narcotic requirements, and 4 of 7 with data had reduced pain (1 of whom was using high-dose intravenous narcotics). No patients experienced functional improvement, and at 6 months, 4 of the 5 who had been ambulatory preoperatively were less mobile. Outcomes tended to be better among patients whose resections were less extensive or limited to zone 3 (anterior pelvis). CONCLUSIONS: Palliative-intent hemipelvectomy provided palliation in a minority of patients, did not improve function, and had high morbidity and mortality. Patients with small anterior pelvic tumor may benefit from palliative hemipelvectomy; for others, less invasive approaches should be considered whenever feasible. Copyright © 2025 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.
Keywords: adult; treatment outcome; aged; bone neoplasms; middle aged; bone tumor; retrospective studies; mortality; palliative care; palliative therapy; retrospective study; cancer center; cancer care facilities; surgery; hemipelvectomy; procedures; humans; human; male; female
Journal Title: Journal of the American College of Surgeons
Volume: 240
Issue: 5
ISSN: 1072-7515
Publisher: Elsevier Science, Inc.  
Date Published: 2025-05-01
Start Page: 797
End Page: 804
Language: English
DOI: 10.1097/xcs.0000000000001256
PUBMED: 39665428
PROVIDER: scopus
PMCID: PMC12003081
DOI/URL:
Notes: Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is Max Vaynrub -- Source: Scopus
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MSK Authors
  1. Amitabh Gulati
    147 Gulati
  2. Garrett Nash
    263 Nash
  3. Michael A Curry
    32 Curry
  4. Maksim Vaynrub
    36 Vaynrub
  5. Dana Mohamed Rashid Omer
    32 Omer
  6. Roni Rosen
    14 Rosen
  7. Varun Aysola
    3 Aysola
  8. Erin Jinna Pamaran Santos
    1 Santos