Consensus nomenclature for radionuclide therapy: Initial recommendations from Nuclear Medicine Global Initiative Journal Article


Authors: Al-Ibraheem, A.; Scott, A. M.; Abdlkadir, A. S.; Vrachimis, A.; Lamoureux, F.; Trujillo, P. B.; Bailey, D. L.; More, S.; Giammarile, F.; Kumar, R.; Nonnekens, J.; Cutler, C. S.; Urbain, J. L. C.; Dibble, E. H.; Sathekge, M. M.; Bomanji, J.; Cerci, J. J.; Thomas, E.; Small, W.; Louw, L.; Hyun, J. O.; Lee, S. T.; Nadel, H.; Jacene, H.; Watabe, T.; Bom, H. H. S.; Bouyoucef, S. E.; Weston, C.; Wadsley, J.; Irwin, A. G.; Croasdale, J.; Zanzonico, P.; Paez, D.; Ghesani, M.
Article Title: Consensus nomenclature for radionuclide therapy: Initial recommendations from Nuclear Medicine Global Initiative
Abstract: Since its inception in 2012, the Nuclear Medicine Global Initiative (NMGI) of the Society of Nuclear Medicine and Molecular Imaging has played an important role in addressing significant challenges in the field of nuclear medicine and molecular imaging. The first 3 projects were dedicated to standardizing pediatric nuclear medicine practices, addressing the global challenges of radionuclide access and availability, and assessing the educational and training initiatives on theranostics across the globe. These efforts aimed to advance human health, foster worldwide educational collaboration, and standardize procedural guidelines to enhance quality and safety in nuclear medicine practice. In its latest project, NMGI aimed to develop a unified nomenclature for systemic radionuclide therapy in nuclear medicine, addressing the diverse terminology currently used. An online survey was distributed to NMGI member organizations, drawing participation from various geographical locations and disciplines. The survey anonymously collected responses from physicians, physicists, scientists, radiopharmacists, radiopharmaceutical scientists, dosimetrists, technologists, and nurse managers, totaling 240 responses from 30 countries. Findings revealed a prevailing use of the term targeted radionuclide therapy for radionuclide therapy, with 52% of respondents expressing a preference for this term. In contrast, approximately 37% favored “radiopharmaceutical therapy,” whereas 11% favored “molecular radionuclide therapy.” Other key terms under the umbrella of targeted radionuclide therapy were also discussed to achieve a consensus on terminology. NMGI efforts to standardize terminology in this dynamic and fluid field should improve communication within the field, better reflect the technology used, enable comparison of results, and ultimately lead to improved patient outcomes. COPYRIGHT © 2025 by the Society of Nuclear Medicine and Molecular Imaging.
Keywords: bone metastasis; consensus; radiotherapy; palliative therapy; questionnaire; prostate specific membrane antigen; radioactive iodine; neuroblastoma; systematic review; arthritis; tumor cell; terminology as topic; nuclear medicine; nomenclature; thyroid cancer; radioisotope; hyperthyroidism; pheochromocytoma; randomized controlled trial (topic); graves disease; radioembolization; radionuclide therapy; humans; human; article; metastatic castration resistant prostate cancer; synovectomy; consensus nomenclature; nmgi; terminology consensus; trt
Journal Title: Journal of Nuclear Medicine
Volume: 66
Issue: 5
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2025-05-01
Start Page: 757
End Page: 763
Language: English
DOI: 10.2967/jnumed.124.269215
PUBMED: 40147850
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Pat B Zanzonico
    355 Zanzonico
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