Recommended clinical context and patient context data elements for liquid biopsy data submitted to data repositories and data commons Guidelines
| Authors: | Grossman, R. L.; Vinson, J.; Bain, E.; Bisselou, K.; Chandan, S.; Compton, C.; Hu, J.; Johann, D. J.; Jones, F.; Jones, G.; LeBlang, S.; Lee, J. S. H.; Lichtenberg, T.; Lockwood, C. M.; Lyle, J.; Martini, J. F.; Merker, J. D.; Saunders, L.; Scher, H.; Somiari, S.; You, J.; Leiman, L. C. |
| Title: | Recommended clinical context and patient context data elements for liquid biopsy data submitted to data repositories and data commons |
| Abstract: | In 2020, BLOODPAC recommended 11 pre-analytical minimal technical data elements for collection and submission of liquid biopsy data to public databases. This article expands on that work by recommending 22 clinical context and 10 patient context data elements. These elements, essential for liquid biopsy data submitted to repositories like the BLOODPAC Data Commons, cover tumor characteristics, disease progression, and patient demographics, supporting biomarker validation, research, and clinical trials. © 2025 The Author(s). Clinical and Translational Science published by Wiley Periodicals LLC on behalf of American Society for Clinical Pharmacology and Therapeutics. |
| Keywords: | overall survival; neoplasm; neoplasms; biological marker; pathology; data base; tumor marker; blood; disease progression; diagnosis; physician; clinical decision making; factual database; databases, factual; disease exacerbation; procedures; humans; human; male; female; article; circulating tumor dna; electronic health record; common data elements; liquid biopsy; biomarkers, tumor; clinical context data elements; data commons; patient context data elements |
| Journal Title: | CTS-Clinical and Translational Science |
| Volume: | 18 |
| Issue: | 4 |
| ISSN: | 1752-8054 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2025-04-01 |
| Start Page: | e70227 |
| Language: | English |
| DOI: | 10.1111/cts.70227 |
| PUBMED: | 40261285 |
| PROVIDER: | scopus |
| PMCID: | PMC12013509 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
