A first-in-human phase 1 study of LY3866288 (LOXO-435), a potent, highly isoform-selective FGFR3 inhibitor (FGFR3i) in advanced solid tumors with FGFR3 alterations: Initial results from FORAGER-1 Meeting Abstract


Authors: Iyer, G.; Ebi, H.; Cook, N.; Gao, X.; Kitano, S.; Matsubara, N.; Reimers, M. A.; Siefker-Radtke, A. O.; Kim, M.; Galsky, M. D.; Robbrecht, D. G.; Guo, J.; Eigl, B. J.; Schaverien, C.; Butts, B.; Yuen, E.; Szymczak, S.; Zhao, X.; Widau, R. C.; Drakaki, A.
Abstract Title: A first-in-human phase 1 study of LY3866288 (LOXO-435), a potent, highly isoform-selective FGFR3 inhibitor (FGFR3i) in advanced solid tumors with FGFR3 alterations: Initial results from FORAGER-1
Meeting Title: 2025 ASCO Genitourinary Cancers Symposium
Journal Title: Journal of Clinical Oncology
Volume: 43
Issue: 5 Suppl.
Meeting Dates: 2025 Feb 13-15
Meeting Location: San Francisco, CA
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2025-02-10
Language: English
ACCESSION: WOS:001454740400007
DOI: 10.1200/JCO.2025.43.5_suppl.662
PROVIDER: wos
Notes: Meeting Abstract: 662 -- Source: Wos
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  1. Gopakumar Vasudeva Iyer
    342 Iyer