Acute promyelocytic leukemia: Molecular genetics, mouse models and targeted therapy Book Whole


Editors: Pandolfi, P. P.; Vogt, P. K.
Title: Acute promyelocytic leukemia: Molecular genetics, mouse models and targeted therapy
Title Series: Current Topics in Microbiology and Immunology
Abstract: This 276-page hardcover book, entitled "Acute Promyelocytic Leukemia: Molecular Generics, Mouse Models and Targeted Therapy", is volume 313 in the Current Topics in Microbiology and Immunology series, and summarizes some of the most recent progress made in elucidating the pathogenesis of acute promyelocytic leukemia and the treatment of this form of leukemia. This volume consists of 13 individually-authored and referenced chapters, written in English. Topics covered include: mouse models of acute promyelocytic leukemia (APL); the PLZF gene of t(11;17)-associated APL; emerging role for microRNAs in APL; treatment of APL by retinoids, histone deacetylase inhibitors, monoclonal antibodies, peptide interference and arsenic trioxide; front line clinical trials and minimal residual disease monitoring in APL; and, the design of selective and non-selective combination therapy for APL. A subject index follows the final chapter. This volume includes 16 illustrations, 9 of which are in color, and 12 tables. This book will be of interest to students and researchers in oncology, immunology, genetics and pharmacology.
Volume: 313
ISBN: 978-3-540-34592-3
Publisher: Springer Verlag  
Publication Place: Berlin, Germany
Date Published: 2007-01-01
Total Pages: 273
Language: English
ACCESSION: BIOSIS:PREV200700280793
PROVIDER: biosis
DOI: 10.1007/978-3-540-34594-7
Notes: --- - Book - Heidelberger platz 3, d-14197 berlin, germany - "Source: Biosis"
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