Surgical management of rare tumors (part 1) Review
| Authors: | Stetson, A.; Saluja, S.; Cameron, D. B.; Mansfield, S. A.; Polites, S. F.; Honeyman, J. N.; Dahl, J. P.; Austin, M. T.; Aldrink, J. H.; Christison-Lagay, E. R. |
| Review Title: | Surgical management of rare tumors (part 1) |
| Abstract: | With an annual cumulative occurrence of approximately 15,000 in North America, all childhood cancers are rare. Very rare cancers as defined by both the European Cooperative Study Group for Rare Pediatric Cancers and the Children's Oncology Group fall into two principal categories: those so uncommon (fewer than 2 cases/million) that their study is challenging even through cooperative group efforts (e.g., pleuropulmonary blastoma and desmoplastic small round cell tumor) and those that are far more common in adults and therefore rarely studied in children (e.g., thyroid, melanoma, and gastrointestinal stromal tumor). Treatment strategies for these latter tumors are typically based on adult guidelines, although the pediatric variants of these tumors may harbor different genetic signatures and demonstrate different behavior. If melanoma and differentiated thyroid cancer are excluded, other rare cancer types account for only 2% of the cancers in children aged 0 to 14. This article highlights several of the most common rare tumor types. © 2024 Wiley Periodicals LLC. |
| Keywords: | adolescent; adult; child; human tissue; preschool child; aged; child, preschool; review; neoplasm; neoplasms; gastrointestinal stromal tumor; melanoma; practice guideline; childhood cancer; colorectal carcinoma; infant; diagnosis; surgery; clinical practice guideline; drug therapy; gist; thyroid papillary carcinoma; north america; rare disease; desmoplastic small round cell tumor; rare diseases; differentiated thyroid cancer; papillary thyroid cancer; gi stromal tumor; humans; human; male; female; pleuropulmonary blastoma; childhood acute lymphoblastic leukemia; infrequent tumor; pediatric colorectal carcinoma; pediatric rare tumor |
| Journal Title: | Pediatric Blood and Cancer |
| Volume: | 72 |
| Issue: | S2 |
| ISSN: | 1545-5009 |
| Publisher: | Wiley Periodicals, Inc |
| Date Published: | 2025-04-01 |
| Start Page: | e31287 |
| Language: | English |
| DOI: | 10.1002/pbc.31287 |
| PUBMED: | 39185712 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
