Top ten tips palliative care clinicians should know about interpreting a clinical trial Editorial
| Authors: | Gurgenci, T.; O’Leary, C.; Hui, D.; Yennu, S.; Bruera, E.; Davis, M.; Agar, M. R.; Zimmermann, C.; Philip, J.; Mercadante, S.; Hardy, J.; Rosa, W. E.; Good, P. |
| Title: | Top ten tips palliative care clinicians should know about interpreting a clinical trial |
| Abstract: | Evidence-based practice is foundational to high-quality palliative care delivery. However, the clinical trials that compose the evidence base are often methodologically imperfect. Applying their conclusions without critical application to the clinical practice context can harm patients. The tips provided can help clinicians infer judiciously from clinical trial results and avoid credulously accepting findings without critique. We suggest that statistical and mathematical expertise is unnecessary, but rather a keen curiosity about investigators’ rationale for certain design choices and how these choices can affect results is key. For a more comprehensive understanding of clinical trials, this article can be used with the authors’ corresponding ten tips article that focuses on designing a clinical trial. Copyright 2025, Mary Ann Liebert, Inc., publishers. |
| Keywords: | clinical trial; clinical practice; evidence-based medicine; palliative care; randomized controlled trial; palliative therapy; evidence based practice; clinical trials; clinician; data interpretation; human; article; quality of data; randomized control trials |
| Journal Title: | Journal of Palliative Medicine |
| Volume: | 28 |
| Issue: | 4 |
| ISSN: | 1096-6218 |
| Publisher: | Mary Ann Liebert, Inc |
| Date Published: | 2025-04-01 |
| Start Page: | 517 |
| End Page: | 523 |
| Language: | English |
| DOI: | 10.1089/jpm.2024.0258 |
| PUBMED: | 39046924 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Source: Scopus |
