Sex differences in peripheral vascular disease: A scientific statement from the American Heart Association Review


Authors: Kim, E. S. H.; Arya, S.; Bryce, Y.; Gornik, H. L.; Long, C. A.; McDermott, M. M.; Pollak, A. W.; Lopez Rowe, V.; Sullivan, A. E.; Whipple, M. O.; on behalf of the American Heart Association Council on Peripheral Vascular Disease; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Genomic and Precision Medicine; Council on Quality of Care and Outcomes Research; Stroke Council
Review Title: Sex differences in peripheral vascular disease: A scientific statement from the American Heart Association
Abstract: Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been well described; however, the bulk of the literature has focused on heart disease in women. Data on sex differences in peripheral vascular disease are ill defined, and there is a need to report and understand those sex-related differences to mitigate adverse outcomes related to those disparities. Although peripheral vascular disease is a highly diverse group of disorders affecting the arteries, veins, and lymphatics, this scientific statement focuses on disorders affecting the peripheral arteries to include the aorta and its branch vessels. The purpose of this scientific statement is to report the current status of sex-based differences and disparities in peripheral vascular disease and to provide research priorities to achieve health equity for women with peripheral vascular disease. © 2025 American Heart Association, Inc.
Keywords: clinical article; review; united states; heart disease; risk factors; vascularization; risk factor; adverse outcome; drug combination; cardiovascular disease; peripheral vascular disease; diagnosis; medical society; sex difference; epidemiology; sex factors; health status disparities; therapy; health disparity; sex characteristics; women; vasculitis; carotid artery disease; peripheral vascular diseases; aneurysm; drug comparison; carotid artery diseases; peripheral arterial disease; humans; human; male; female; aha scientific statements; sex factor; sexual characteristics; american heart association
Journal Title: Circulation
Volume: 151
Issue: 14
ISSN: 0009-7322
Publisher: Lippincott Williams & Wilkins  
Date Published: 2025-04-08
Start Page: e877
End Page: e904
Language: English
DOI: 10.1161/cir.0000000000001310
PUBMED: 40066579
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Swarn Vijay Arya
    2 Arya