Dexamethasone is associated with reduced frequency and intensity of cytokine release syndrome compared with alternative corticosteroid regimens as premedication for glofitamab in patients with relapsed/refractory large B-cell lymphoma Research Letter


Authors: Falchi, L.; Hutchings, M.; Carlo-Stella, C.; Morschhauser, F.; Dickinson, M.; Cartron, G.; Khan, C.; Tani, M.; Martinez-Lopez, J.; Bartlett, N. L.; Salar, A.; Brody, J. D.; Leppä, S.; Berthier, A.; Kallemeijn, M.; Relf, J.; Tchaleu, F. B.; Lundberg, L.; Bachy, E.
Title: Dexamethasone is associated with reduced frequency and intensity of cytokine release syndrome compared with alternative corticosteroid regimens as premedication for glofitamab in patients with relapsed/refractory large B-cell lymphoma
Keywords: adult; cancer chemotherapy; controlled study; aged; major clinical study; overall survival; prednisone; drug efficacy; drug safety; cancer grading; letter; progression free survival; multiple cycle treatment; phase 2 clinical trial; dexamethasone; histology; intensive care unit; prednisolone; paracetamol; multicenter study; methylprednisolone; phase 1 clinical trial; corticosteroid; non-hodgkin lymphoma; artificial ventilation; diphenhydramine; premedication; cytokine release syndrome; overall response rate; diffuse large b cell lymphoma; tocilizumab; very elderly; human; male; female; article; obinutuzumab; positron emission tomography-computed tomography; ecog performance status; glofitamab
Journal Title: Haematologica
Volume: 110
Issue: 4
ISSN: 0390-6078
Publisher: Ferrata Storti Foundation  
Date Published: 2025-04-01
Start Page: 999
End Page: 1004
Language: English
DOI: 10.3324/haematol.2024.286257
PUBMED: 39605203
PROVIDER: scopus
PMCID: PMC11959244
DOI/URL:
Notes: Letter -- MSK corresponding author is Lorenzo Falchi -- Source: Scopus
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