Role of MRI in assessing the feasibility of fertility-sparing treatments for early-stage endometrial and cervical cancers Review

  


Authors: Lee, M.; Causa Andrieu, P. I.; Nougaret, S.; Russo, L.; Moufarrij, S.; Mueller, J. J.; Abu-Rustum, N. R.; Menias, C. O.; Lakhman, Y.
Review Title: Role of MRI in assessing the feasibility of fertility-sparing treatments for early-stage endometrial and cervical cancers
Abstract: Fertility-sparing treatment (FST) has become a key aspect of managing gynecologic cancers in reproductive-age patients who wish to preserve fertility. Several leading clinical societies, including the European Society of Gynecological Oncology, the European Society for Radiotherapy and Oncology, the European Society of Pathology, and the European Society of Human Reproduction and Embryology, have published evidence-based guidelines on fertility-sparing strategies and posttreatment surveillance of patients with early-stage gynecologic cancers, in particular endometrial and cervical cancers. These guidelines highlight MRI as essential to initial patient selection and follow-up. Properly tailored pelvic MRI protocols and clear MRI reports are key to performing accurate staging, assessing eligibility, and confirming the initial and ongoing feasibility of FST. Accordingly, radiologists, particularly those specializing in gynecologic imaging, play a critical role in the multidisciplinary approach to FST. They should be well-versed in FST eligibility criteria and key MRI findings before and after FST, ensuring these details are comprehensively communicated in structured MRI reports. © American Roentgen Ray Society.
Keywords: adult; human tissue; review; patient selection; nuclear magnetic resonance imaging; follow up; endometrial cancer; endometrium cancer; radiotherapy; evidence based practice; radiologist; uterine cervix cancer; diagnosis; surgery; drug dose; clinical practice guideline; drug therapy; fertility; therapy; mri; endometrium; cervical cancer; oral drug administration; fertility preservation; female genital tract cancer; human; female; mri scanner
Journal Title: American Journal of Roentgenology
Volume: 224
Issue: 3
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2025-03-01
Start Page: e2432157
Language: English
DOI: 10.2214/ajr.24.32157
PUBMED: 39772587
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-105002789375&doi=10.2214%2fAJR.24.32157&partnerID=40&md5=c8ea73d1ea138e2086160860656b8c6e
Notes: Review -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- MSK corresponding author is Yulia Lakhman -- Source: Scopus
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MSK Authors
  1. Nadeem Abu-Rustum
    888 Abu-Rustum
  2. Jennifer Jean Mueller
    186 Mueller
  3. Sara Maria Moufarrij
    20 Moufarrij
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