Successful targeted therapy of refractory pediatric ETV6-NTRK3 fusion-positive secretory breast carcinoma Journal Article


Authors: Shukla, N.; Roberts, S. S.; Baki, M. O.; Mushtaq, Q.; Goss, P. E.; Park, B. H.; Gundem, G.; Tian, K.; Geiger, H.; Redfield, K.; Behr, G.; Benayed, R.; Zehir, A.; Hechtman, J. F.; Darnell, R. B.; Papaemmanuil, E.; Ladanyi, M.; Ku, N.; Kung, A. L.; Baselga, J.; Drilon, A.; Hyman, D. M.
Article Title: Successful targeted therapy of refractory pediatric ETV6-NTRK3 fusion-positive secretory breast carcinoma
Keywords: immunohistochemistry; adolescent; clinical article; human tissue; gene mutation; human cell; promoter region; histopathology; case report; doxorubicin; fluorouracil; recommended drug dose; gemcitabine; paclitaxel; lymph node metastasis; lymph node dissection; gene; carboplatin; dacarbazine; multiple cycle treatment; cyclophosphamide; ifosfamide; docetaxel; axillary lymph node; lung metastasis; breast carcinoma; fusion gene; telomerase reverse transcriptase; mesna; molecularly targeted therapy; bangladesh; tert gene; human; female; priority journal; article; whole genome sequencing; ntrk3 gene; vinorelbine tartrate; larotrectinib; etv6 gene; etv6 ntrk3 gene
Journal Title: JCO Precision Oncology
Volume: 2017
Issue: 1
ISSN: 2473-4284
Publisher: American Society of Clinical Oncology  
Date Published: 2017-12-01
Language: English
DOI: 10.1200/po.17.00034
PROVIDER: scopus
PMCID: PMC5880290
PUBMED: 29623306
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Neerav Shukla -- Source: Scopus
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MSK Authors
  1. Marc Ladanyi
    1326 Ladanyi
  2. David Hyman
    354 Hyman
  3. Ahmet Zehir
    343 Zehir
  4. Neerav Shukla
    159 Shukla
  5. Alexander Edward Drilon
    632 Drilon
  6. Stephen Stacy Roberts
    107 Roberts
  7. Jose T Baselga
    484 Baselga
  8. Jaclyn Frances Hechtman
    212 Hechtman
  9. Rym Benayed
    188 Benayed
  10. Andrew L Kung
    96 Kung
  11. Gunes Gundem
    56 Gundem
  12. Gerald Gideon Behr
    29 Behr