Authors: | Florez, N.; Patel, S. P.; Wakelee, H.; Bazhenova, L.; Massarelli, E.; Salgia, R.; Stiles, B.; Peters, S.; Malhotra, J.; Gadgeel, S. M.; Nieva, J. J.; Afkhami, M.; Hirsch, F. R.; Gubens, M.; Cascone, T.; Levy, B.; Sabari, J.; Husain, H.; Ma, P. C.; Backhus, L. M.; Iyengar, P.; Lee, P.; Miller, R.; Sands, J.; Kim, E. |
Review Title: | Proceedings of the 1st biannual Bridging the Gaps in Lung Cancer conference |
Abstract: | Lung cancer is the leading cause of cancer death in the US and globally. The mortality from lung cancer has been declining, due to a reduction in incidence and advances in treatment. Although recent success in developing targeted and immunotherapies for lung cancer has benefitted patients, it has also expanded the complexity of potential treatment options for health care providers. To aid in reducing such complexity, experts in oncology convened a conference (Bridging the Gaps in Lung Cancer) to identify current knowledge gaps and controversies in the diagnosis, treatment, and outcomes of various lung cancer scenarios, as described here. Such scenarios relate to biomarkers and testing in lung cancer, small cell lung cancer, EGFR mutations and targeted therapy in non-small cell lung cancer (NSCLC), early-stage NSCLC, KRAS/BRAF/MET and other genomic alterations in NSCLC, and immunotherapy in advanced NSCLC. © The Author(s) 2024. |
Keywords: | genetics; mutation; carcinoma, non-small-cell lung; lung neoplasms; epidermal growth factor receptor; pathology; tumor marker; lung tumor; immunotherapy; therapy; non small cell lung cancer; molecularly targeted therapy; molecular targeted therapy; procedures; controversies; erbb receptors; clinical decision-making; humans; human; biomarkers, tumor; lung cancer treatment; lung cancer diagnosis; lung cancer management; unanswered questions |
Journal Title: | The Oncologist |
Volume: | 30 |
Issue: | 2 |
ISSN: | 1083-7159 |
Publisher: | Oxford University Press |
Date Published: | 2025-02-01 |
Start Page: | oyae228 |
Language: | English |
DOI: | 10.1093/oncolo/oyae228 |
PUBMED: | 39237103 |
PROVIDER: | scopus |
PMCID: | PMC11883156 |
DOI/URL: | |
Notes: | Article -- Source: Scopus |