Vaccines as targeted cancer therapy Book Section


Authors: Perales, M. A.; Wolchok, J. D.; Kaufman, H. L.
Editors: Kaufman, H. L.; Wadler, S.; Antman, K.
Article/Chapter Title: Vaccines as targeted cancer therapy
Title Series: Cancer Drug Discovery and Development
Abstract: The identification of antigens on tumor cells has led to significant contributions to the field of immunotherapy. One of the most active areas under investigation in cancer immunotherapy is the development of vaccines against melanoma antigens. Induction of immunity against tumor antigens can follow multiple routes using different mechanisms. Crucial to the development of active immunization and other immunotherapies are the discovery and understanding of the molecular identity of tumor antigens and the mechanisms involved in tumor immunity. In this chapter, we will discuss strategies to induce active immunity against tumors, using melanoma as a paradigm for targeted vaccine therapy.
Book Title: Molecular Targeting in Oncology
ISBN: 978-1-58829-577-4
Publisher: Humana Press Inc  
Publication Place: Totowa, NJ
Date Published: 2008-01-01
Start Page: 447
End Page: 469
Language: English
ACCESSION: BIOSIS:PREV200800346460
PROVIDER: biosis
DOI: 10.1007/978-1-59745-337-0_19
Notes: --- - Book Chapter: 19 - "Source: Biosis"
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  1. Jedd D Wolchok
    905 Wolchok
  2. Miguel-Angel Perales
    913 Perales