Critical review of ketogenic diet throughout the cancer continuum for neuroglioma: Insights from a Medical Nutrition Therapy (MNT) perspective Review
| Authors: | Thomopoulos-Titomihelakis, K. D.; Sach, H.; McCann, R.; Zhang, Q.; Kurnit, S.; Codoni De Juan, G.; Rushing, A. |
| Review Title: | Critical review of ketogenic diet throughout the cancer continuum for neuroglioma: Insights from a Medical Nutrition Therapy (MNT) perspective |
| Abstract: | Purpose of Review: A Ketogenic diet (KD; a diet comprised of 75% fat, 20% protein and 5% carbohydrates) has gained much popularity in recent years, especially regarding neurogliomas (or “gliomas”). This review critically assesses literature on the application of KD throughout the cancer continuum from a Medical Nutrition Therapy (MNT) perspective. Recent Findings: 2021 revised classification standards for Central Nervous System (CNS) tumors are available. Despite research on KD and CNS tumors increasing, the role and benefits of MNT to augment side effects of traditional treatment and KD throughout the cancer continuum remain unclear. Summary: Glioma cancer survivors may benefit from a KD. It is a challenging, yet feasible non-pharmacological adjuvant approach. More research is needed regarding KD for prevention and post-treatment of glioma. Standard guidelines regarding macronutrient composition of KD for glioma are warranted. The need and benefits of nutritional guidance provided by a Registered Dietitian Nutritionist (RD or RDNs) during adherence to KD are understated. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025. |
| Keywords: | review; brain tumor; glioma; brain neoplasms; radiotherapy; practice guideline; central nervous system tumor; central nervous system; cancer survivor; diet; survivorship; diet therapy; clinical practice guideline; drug therapy; therapy; prevention; cancer survivorship; commercial phenomena; procedures; humans; human; dietitian; pharmacoeconomics; malignant neoplasm; diet, ketogenic; ketogenic diet; intermittent fasting; medical nutrition therapy; neuroglioma; nutrition therapy; macronutrient; nasal glioma |
| Journal Title: | Current Nutrition Reports |
| Volume: | 14 |
| ISSN: | 2161-3311 |
| Publisher: | Springer Healthcare |
| Date Published: | 2025-01-30 |
| Start Page: | 24 |
| Language: | English |
| DOI: | 10.1007/s13668-025-00609-4 |
| PUBMED: | 39885002 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Erratum issued: 10.1007/s13668-025-00625-4 -- MSK corresponding author is Kristina Thomopoulos-Titomihelakis -- Source: Scopus |
