Feasibility and acceptability of a mindfulness app-based intervention among patients with metastatic renal cell carcinoma: A multinational study Journal Article
| Authors: | Bergerot, C. D.; Bergerot, P. G.; Philip, E. J.; Malhotra, J.; Castro, D. V.; Govindarajan, A.; Fuzita, W. H.; da Silva França, M. V.; de Azeredo, A. C.; dos Anjos, G. M.; de Araujo, R.; Hsu, J.; Chawla, N.; Chehrazi-Raffle, A.; Buso, M. M.; Saab, B.; Carlson, L. E.; Pal, S. K. |
| Article Title: | Feasibility and acceptability of a mindfulness app-based intervention among patients with metastatic renal cell carcinoma: A multinational study |
| Abstract: | Background: Patients with metastatic renal cell carcinoma (mRCC) experience emotional distress and limited supportive care access. This study assesses a mindfulness app’s feasibility, acceptability, and preliminary efficacy in improving emotional symptoms, trait mindfulness, and overall quality of life for patients with mRCC on immunotherapy. Methods: This multinational study recruited patients with mRCC undergoing immunotherapy from Brazil and the United States. Participants were required to engage in mindfulness app-based activities for 20–30 min daily, at least 4 days per week, over a 4-week period. Assessments were conducted at weeks 0, 2, 4, and 12 to evaluate emotional symptoms (PROMIS-Anxiety and Depression, Fear of Cancer Recurrence-7), fatigue (Brief Fatigue Inventory), trait mindfulness (Mindfulness Attention Awareness Scale), and quality of life (Functional Assessment of Chronic Illness Therapy-General). Self-reported data were used to assess adherence. Linear mixed-effects models were used to evaluate changes over time for the measured outcomes. Results: Among 50 patients with mRCC, the feasibility of this intervention was demonstrated; 96% of patients were assessed at week 4, with high adherence rates reported by 75% of patients. Participants expressed positive feedback on the smartphone-based approach. Significant improvements were observed in emotional symptoms, fatigue, and quality of life scores from baseline to post-intervention (P = .001 for each), suggesting the positive impact of this intervention. Conclusion: Our findings provide encouraging evidence for the feasibility and acceptability of a mindfulness app-based intervention among patients with mRCC. This intervention may offer a viable and accessible means of providing psychosocial support to patients with mRCC. © The Author(s) 2025. Published by Oxford University Press. |
| Journal Title: | The Oncologist |
| Volume: | 30 |
| Issue: | 1 |
| ISSN: | 1083-7159 |
| Publisher: | Oxford University Press |
| Date Published: | 2025-01-17 |
| Start Page: | oyae309 |
| Language: | English |
| DOI: | 10.1093/oncolo/oyae309 |
| PUBMED: | 39820635 |
| PROVIDER: | scopus |
| PMCID: | PMC11740315 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
Related MSK Work