Advances and challenges in precision imaging Review
| Authors: | Hricak, H.; Mayerhoefer, M. E.; Herrmann, K.; Lewis, J. S.; Pomper, M. G.; Hess, C. P.; Riklund, K.; Scott, A. M.; Weissleder, R. |
| Review Title: | Advances and challenges in precision imaging |
| Abstract: | Technological innovations in genomics and related fields have facilitated large sequencing efforts, supported new biological discoveries in cancer, and spawned an era of liquid biopsy biomarkers. Despite these advances, precision oncology has practical constraints, partly related to cancer's biological diversity and spatial and temporal complexity. Advanced imaging technologies are being developed to address some of the current limitations in early detection, treatment selection and planning, drug delivery, and therapeutic response, as well as difficulties posed by drug resistance, drug toxicity, disease monitoring, and metastatic evolution. We discuss key areas of advanced imaging for improving cancer outcomes and survival. Finally, we discuss practical challenges to the broader adoption of precision imaging in the clinic and the need for a robust translational infrastructure. © 2025 Elsevier Ltd |
| Keywords: | treatment response; genetics; review; nonhuman; neoplasm; neoplasms; biological marker; diagnostic imaging; tumor marker; drug toxicity; drug delivery system; personalized medicine; disease surveillance; biodiversity; procedures; humans; human; precision medicine; liquid biopsy; biomarkers, tumor; personalized cancer therapy |
| Journal Title: | Lancet Oncology |
| Volume: | 26 |
| Issue: | 1 |
| ISSN: | 1470-2045 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2025-01-01 |
| Start Page: | e34 |
| End Page: | e45 |
| Language: | English |
| DOI: | 10.1016/s1470-2045(24)00395-4 |
| PUBMED: | 39756454 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
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