International Skin Imaging Collaboration-Designated Diagnoses (ISIC-DX): Consensus terminology for lesion diagnostic labeling Journal Article
| Authors: | Scope, A.; Liopyris, K.; Weber, J.; Barnhill, R. L.; Braun, R. P.; Curiel-Lewandrowski, C. N.; Elder, D. E.; Ferrara, G.; Grant-Kels, J. M.; Jeunon, T.; Lallas, A.; Lin, J. Y.; Marchetti, M. A.; Marghoob, A. A.; Navarrete-Dechent, C.; Pellacani, G.; Soyer, H. P.; Stratigos, A.; Thomas, L.; Kittler, H.; Rotemberg, V.; Halpern, A. C. |
| Article Title: | International Skin Imaging Collaboration-Designated Diagnoses (ISIC-DX): Consensus terminology for lesion diagnostic labeling |
| Abstract: | Background: A common terminology for diagnosis is critically important for clinical communication, education, research and artificial intelligence. Prevailing lexicons are limited in fully representing skin neoplasms. Objectives: To achieve expert consensus on diagnostic terms for skin neoplasms and their hierarchical mapping. Methods: Diagnostic terms were extracted from textbooks, publications and extant diagnostic codes. Terms were hierarchically mapped to super-categories (e.g. ‘benign’) and cellular/tissue-differentiation categories (e.g. ‘melanocytic’), and appended with pertinent-modifiers and synonyms. These terms were evaluated using a modified-Delphi consensus approach. Experts from the International-Skin-Imaging-Collaboration (ISIC) were surveyed on agreement with terms and their hierarchical mapping; they could suggest modifying, deleting or adding terms. Consensus threshold was >75% for the initial rounds and >50% for the final round. Results: Eighteen experts completed all Delphi rounds. Of 379 terms, 356 (94%) reached consensus in round one. Eleven of 226 (5%) benign-category terms, 6/140 (4%) malignant-category terms and 6/13 (46%) indeterminate-category terms did not reach initial agreement. Following three rounds, final consensus consisted of 362 terms mapped to 3 super-categories and 41 cellular/tissue-differentiation categories. Conclusions: We have created, agreed upon, and made public a taxonomy for skin neoplasms and their hierarchical mapping. Further study will be needed to evaluate the utility and completeness of the lexicon. © 2024 European Academy of Dermatology and Venereology. |
| Keywords: | controlled study; human tissue; major clinical study; histopathology; diagnostic accuracy; consensus; melanoma; actinic keratosis; basal cell carcinoma; skin; skin tumor; delphi study; nomenclature; dysplastic nevus; tissue differentiation; productivity; dermatologist; diagnostic test accuracy study; cheilitis; sclerosing agent; human; article; international skin imaging collaboration; melanocytic proliferation; adnexal epithelial proliferation; attention deficit hyperactivity disorder; atypical melanocytic neoplasm; benign proliferation; cellular tissue differentiation; consensus terminology; dermato pathologist; hierarchical mapping; lesion diagnostic labeling; malignant category term |
| Journal Title: | Journal of the European Academy of Dermatology and Venereology |
| Volume: | 39 |
| Issue: | 1 |
| ISSN: | 0926-9959 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2025-01-01 |
| Start Page: | 117 |
| End Page: | 125 |
| Language: | English |
| DOI: | 10.1111/jdv.20055 |
| PUBMED: | 38733254 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Source: Scopus |
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