A case study of polypharmacy-induced serotonin syndrome in a cancer patient Journal Article
| Authors: | Zhu, A.; Kuhnly, N.; Chen, L.; Dulu, A. O. |
| Article Title: | A case study of polypharmacy-induced serotonin syndrome in a cancer patient |
| Abstract: | Polypharmacy in cancer care can be complex and detrimental, particularly among younger patients, who can be easily overlooked. This report showcases a 54-year-old woman with cancer, treated for dapsone-induced methemoglobinemia with methylene blue (MB), subsequently developing serotonin syndrome (SS) due to concurrent serotonin-active medications. This case highlights the critical impact of polypharmacy, emphasizing the necessity for acute care providers to diligently assess medication interactions, especially in emergencies. It underscores the importance of considering alternative treatments and the vigilant monitoring of symptoms indicative of adverse drug interactions to ensure patient safety and optimize outcomes in complex therapeutic scenarios. © 2024 American Association of Nurse Practitioners. Unauthorized reproduction of this article is prohibited. |
| Keywords: | middle aged; case report; methylene blue; neoplasm; neoplasms; drug therapy; serotonin syndrome; dapsone; drug interactions; polypharmacy; drug interaction; complication; methemoglobinemia; humans; human; female; medication reconciliation |
| Journal Title: | Journal of the American Association of Nurse Practitioners |
| Volume: | 36 |
| Issue: | 12 |
| ISSN: | 2327-6886 |
| Publisher: | American Association of Nurse Practitioners |
| Date Published: | 2024-12-01 |
| Start Page: | 728 |
| End Page: | 732 |
| Language: | English |
| DOI: | 10.1097/jxx.0000000000001048 |
| PUBMED: | 39051987 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is Nicole Kuhnly -- Source: Scopus |
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