Hemodynamic stability of midazolam versus remimazolam during outpatient genitourinary interventional radiology procedures in a patient with aortic stenosis: A case report Journal Article


Authors: Bui, A.; Serafin, J.; Shah, S.; Barnett, K. M.
Article Title: Hemodynamic stability of midazolam versus remimazolam during outpatient genitourinary interventional radiology procedures in a patient with aortic stenosis: A case report
Abstract: Patients with aortic stenosis (AS) and other significant cardiopulmonary comorbidities are vulnerable to hemodynamic instability during anesthesia. This case report compares the use of remimazolam and midazolam in a 71-year-old man with symptomatic AS, chronic kidney disease, and ischemic cardiomyopathy. The patient underwent multiple short ambulatory interventional radiology procedures. While moderate sedation with midazolam resulted in significant hypotension, use of remimazolam in subsequent procedures demonstrated a stable hemodynamic profile despite increased disease burden. This report highlights the potential advantages of remimazolam compared to midazolam in high-risk patients undergoing interventional radiology procedures. Copyright © 2024 International Anesthesia Research Society.
Keywords: aged; case report; midazolam; drug effect; interventional radiology; benzodiazepine derivative; surgery; radiology, interventional; hemodynamics; hypnotics and sedatives; hypnotic sedative agent; benzodiazepines; humans; human; male; aortic valve stenosis; remimazolam
Journal Title: A and A Practice
Volume: 18
Issue: 12
ISSN: 2575-3126
Publisher: Lippincott Williams & Wilkins  
Date Published: 2024-12-01
Start Page: e01879
Language: English
DOI: 10.1213/xaa.0000000000001879
PUBMED: 39655835
PROVIDER: scopus
PMCID: PMC11636967
DOI/URL:
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PubMed record and PDF. Corresponding MSK author is Kara M. Barnett -- Source: Scopus
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MSK Authors
  1. Kara Michelle Barnett
    17 Barnett
  2. Joanna Serafin
    13 Serafin
  3. Suken H. Shah
    9 Shah