Dosimetric commissioning of a high-resolution CMOS 2D detector array for patient-specific QA of single-isocenter multi-target VMAT stereotactic radiosurgery Journal Article
| Authors: | Teng, C. L.; Lin, S. C.; Lovelock, D. M.; Lim, S. B. |
| Article Title: | Dosimetric commissioning of a high-resolution CMOS 2D detector array for patient-specific QA of single-isocenter multi-target VMAT stereotactic radiosurgery |
| Abstract: | Stereotactic radiosurgery (SRS) using the single-isocenter-multiple-target (SIMT) technique by volumetric modulated arc therapy is increasingly popular for treating multiple brain metastases. However, the complex nature of SIMT SRS necessitates rigorous patient-specific quality assurance (PSQA). This study presents a multi-institutional dosimetric commissioning of a high-resolution complementary metal oxide semiconductor (CMOS) 2D detector array, the myQA SRS device for SIMT SRS PSQA. Basic dosimetric properties such as dose-rate, field-size, energy and angular dependencies were characterized for the CMOS detectors. Additionally, gamma index analyses were performed between the measured dose and the films for nine simulated and clinical plans. The results showed that the CMOS detector was dose-rate, field-size, energy and beam-angle dependent. Specific to SIMT SRS, angular dependence on gantry rotations was invariant to couch rotations but was sensitive to off-isocenter distances. With appropriate dose calibration and angular corrections, myQA SRS showed a high dosimetric correlation with films. The average gamma index pass rates were 99.9 ± 0.03% and 99.2 ± 1.1% at 3%/2 mm/10%thr(global) and 1 mm/1%/10%thr(local) criteria, respectively. The average dose difference between myQA SRS and films was 0.4 ± 1.3%. In conclusion, the CMOS 2D detector array has demonstrated its potential as a reliable tool for PSQA for SIMT SRS. The excellent dosimetric agreement with the films was consistent in multiple institutions, further validating the dosimetric accuracy and reproducibility. It provides a timely alternative to film dosimetry for commissioning and quality assurance. © The Author(s) 2024. Published by Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology. |
| Keywords: | intensity modulated radiation therapy; radiotherapy dosage; calibration; health care quality; radiotherapy, intensity-modulated; quality assurance, health care; radiosurgery; radiometry; radiotherapy planning, computer-assisted; radiochromic film dosimetry; semiconductor; devices; procedures; semiconductors; humans; human; radiotherapy planning system; patient-specific qa; cmos 2d diode array; myqa srs; single isocenter multiple target simt; stereotactic radiosurgery srs |
| Journal Title: | Journal of Radiation Research |
| Volume: | 65 |
| Issue: | 6 |
| ISSN: | 0449-3060 |
| Publisher: | Oxford University Press |
| Date Published: | 2024-11-01 |
| Start Page: | 787 |
| End Page: | 797 |
| Language: | English |
| DOI: | 10.1093/jrr/rrae080 |
| PUBMED: | 39412202 |
| PROVIDER: | scopus |
| PMCID: | PMC11629995 |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PubMed and PDF -- MSK corresponding author is Seng Boh Lim -- Source: Scopus |
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