Comparison of clinical characteristics and outcomes of patients with breast cancer and liver metastases who have or have not undergone radioembolization Journal Article
| Authors: | Bryce, Y.; Annie, F.; Sarkar, D.; Deipolyi, A. R. |
| Article Title: | Comparison of clinical characteristics and outcomes of patients with breast cancer and liver metastases who have or have not undergone radioembolization |
| Abstract: | The purpose of this study was to compare characteristics and outcomes of patients with breast cancer with liver metastasis who had and had not undergone radioembolization. Medical records of patients with breast cancer with liver metastases (4,332 patients who had not undergone radioembolization and 166 patients who had) seen between January 1, 2009, and October 31, 2021, were assessed. Propensity score matching was performed. Patients who underwent radioembolization were significantly younger (47.7 years [SD ± 10.1] vs 52.3 years [SD ± 12.5]; P < .001) and underwent more systemic treatment regimens (8.6 [SD ± 4.1] vs 5.2 [SD ± 3.2]; P < .001). Median survival was longer, in unmatched (67.1 vs 40.7 months; P = .001) and matched (67.1 vs 38.0 months, P = .001) cohorts. Radioembolization was associated with superior survival (P = .002). In conclusion, patients with breast cancer with liver metastases who underwent radioembolization were significantly younger and underwent more treatment regimens. Radioembolization was associated with longer median survival. © 2024 SIR |
| Keywords: | adult; cancer chemotherapy; cancer survival; controlled study; middle aged; major clinical study; clinical feature; systemic therapy; comparative study; antineoplastic agent; metabolism; retrospective study; liver metastasis; glass; estrogen receptor; progesterone receptor; metastatic breast cancer; resin; triple negative breast cancer; clinical outcome; microsphere; propensity score; radioembolization; human; male; female; article; median survival time; positron emission tomography-computed tomography |
| Journal Title: | Journal of Vascular and Interventional Radiology |
| Volume: | 35 |
| Issue: | 12 |
| ISSN: | 1051-0443 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2024-12-01 |
| Start Page: | 1833 |
| End Page: | 1837 |
| Language: | English |
| DOI: | 10.1016/j.jvir.2024.08.019 |
| PUBMED: | 39214381 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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