T-cell immunotherapy for melanoma Review
| Authors: | Mantilla Rosa, C.; Vancheswaran, A.; Ariyan, C. E. |
| Review Title: | T-cell immunotherapy for melanoma |
| Abstract: | This review explores T-cell immunotherapy for melanoma, highlighting immune checkpoint inhibitors (anti-CTLA-4, anti-PD-1, anti-LAG-3), tumor-infiltrating lymphocytes (TILs), and emerging therapies that engineer T cells with specific receptors or T-cell receptors, such as CAR-T and TCR cells, and RNA vaccines. We discuss the history of T-cell immunotherapy, mechanisms of action, and future directions for improving patient outcomes. © 2024 Elsevier Ltd |
| Keywords: | review; side effect; t lymphocyte; tumor associated leukocyte; melanoma; t lymphocyte receptor; drug combination; surgery; drug therapy; cytotoxic t lymphocyte antigen 4; adverse drug reaction; therapy; pharmacology; lymphocyte activation gene 3 protein; immune checkpoint inhibitor; rna vaccine; human; checkpoint inhibitors; chimeric antigen receptor t-cell; unexpected outcome of drug treatment; adoptive t-cell immunotherapy |
| Journal Title: | Surgical Oncology |
| Volume: | 57 |
| ISSN: | 0960-7404 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2024-12-01 |
| Start Page: | 102160 |
| Language: | English |
| DOI: | 10.1016/j.suronc.2024.102160 |
| PROVIDER: | scopus |
| PUBMED: | 39579510 |
| DOI/URL: | |
| Notes: | Source: Scopus |
