Utility of pelvic CT in patients undergoing surveillance for hepatocellular carcinoma: A retrospective multi-institutional study Journal Article


Authors: Shahbazian, H.; Raja, K.; Sirlin, C.; Nemzow, G.; Borhani, A.; Attari, M. M. A.; Kamel, I. R.; Chernyak, V.
Article Title: Utility of pelvic CT in patients undergoing surveillance for hepatocellular carcinoma: A retrospective multi-institutional study
Abstract: Objective: To determine the frequency, characteristics and clinical significance of incidental pelvic findings reported on abdominopelvic CT performed for hepatocellular carcinoma (HCC) surveillance in at-risk patients. Material and methods: This two-center retrospective study received institutional review board approval with a waiver of informed consent. The radiologic reports of the CT exams performed 1/1/2010–2/28/2023 for HCC surveillance were reviewed. Exams were obtained with intravenous contrast material and included hepatic arterial and portal venous phases of the abdomen; images of the pelvis were acquired during the portal venous phase. Reported imaging findings and imaging-related recommendations either by the radiologists or the corresponding caregiver, if present, were retrospectively tabulated. The patient's medical records were reviewed to determine if there were any recommendations that were considered clinically important and culminated in any further interventions or treatments. Results: 259 adults (1st center: mean age, 60 ± 11 years, 49% male and 2nd center: 56.26 ± 6.2 years, 48% male) at risk for HCC underwent 327 abdominopelvic CT exams for HCC surveillance at two centers. A total of 622 pelvic findings (mean, 2.2/ exam) were reported, including 131 bladder, 120 alimentary tract, 133 vascular, 51 gynecologic, 37 prostate, 33 lymph node, 27 inguinal, 44 peritoneal, and 46 skeletal. 52 of 622 reported findings (8.3%) were associated with actionable recommendations. 24 of the 52 actionable recommendations/clinical suggestions were implemented as follows: five complimentary imaging, ten additional laboratory tests, and nine non-imaging recommendations. Of note, only eight applied recommendations culminated in a clinical outcome, which included four urinary tract infection treatments. Conclusion: Pelvic CT findings were associated with a clinical benefit to the patient in 1.3% of exams. These results suggest that pelvic imaging should be omitted from CT-based HCC surveillance. Clinical relevance: Without compromising valuable information, patients undergoing HCC surveillance-CT may not require additional pelvic coverage.
Journal Title: Abdominal Radiology
Volume: 49
Issue: 11
ISSN: 2366-004X
Publisher: Springer  
Date Published: 2024-11-01
Start Page: 4125
End Page: 4130
Language: English
DOI: 10.1007/s00261-024-04362-0
PROVIDER: EBSCOhost
PROVIDER: cinahl plus with full text
DOI/URL:
Notes: Accession Number: 180550639 -- Entry Date: In Process -- Revision Date: 20241101 -- Publication Type: Journal Article -- Journal Subset: Biomedical -- NLM UID: 101674571. -- Source: CINAHL Plus with Full Text
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