The OBSERVE guidelines provide refinement criteria for rodent oncology models Editorial
| Authors: | Ritter, A. C.; Cheleuitte-Nieves, C.; Lipman, N. S. |
| Title: | The OBSERVE guidelines provide refinement criteria for rodent oncology models |
| Abstract: | A consensus statement outlines the best practices to refine animal welfare in rodent models of cancer. Their adoption will allow the standardization of experimental interventions, considering the characteristics of each cancer model, thereby improving the reproducibility and translational value of data obtained in rodents. © Springer Nature Limited 2024. |
| Keywords: | allograft; surgical technique; nonhuman; note; neoplasm; neoplasms; reproducibility; mouse; animal; animals; mice; consensus; pain; animal model; practice guideline; in vivo study; tumor xenograft; oncology; cancer model; carcinogenesis; transgenic animal; disease model; standardization; intervention study; tumor burden; rat; scoring system; distress syndrome; rats; tumor growth; disease models, animal; analgesia; translational research; guidelines as topic; anesthesia; cancer transplantation; perioperative care; adverse event; animal welfare; isograft; animal euthanasia; animal testing refinement; clinical monitoring; rodent model; implementation science |
| Journal Title: | Nature Protocols |
| Volume: | 19 |
| Issue: | 10 |
| ISSN: | 1754-2189 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2024-10-01 |
| Start Page: | 2831 |
| End Page: | 2832 |
| Language: | English |
| DOI: | 10.1038/s41596-024-01008-9 |
| PUBMED: | 38982228 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Note -- Source: Scopus |
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