From neoadjuvant to organ-sparing immunotherapy for colorectal cancer Editorial
| Authors: | Rousseau, B.; Cercek, A.; Diaz, L. A. Jr |
| Title: | From neoadjuvant to organ-sparing immunotherapy for colorectal cancer |
| Abstract: | In a new study, neoadjuvant immunotherapy led to major pathological responses in patients with locally advanced colon cancer harboring mismatch repair deficiency — and emerging evidence suggests that organ-sparing approaches may also be feasible. © Springer Nature America, Inc. 2024. |
| Keywords: | cancer survival; advanced cancer; drug efficacy; drug safety; treatment duration; note; neoadjuvant therapy; colorectal cancer; t lymphocyte; ipilimumab; cancer immunotherapy; tumor regression; b lymphocyte; colorectal neoplasms; immunology; feasibility study; immunotherapy; conservative treatment; colorectal tumor; mismatch repair; antigen recognition; adaptive immunity; cytotoxic t lymphocyte antigen 4; immunosurveillance; therapy; programmed death 1 receptor; immunological memory; procedures; long term survival; nivolumab; organ sparing treatments; humans; human; cxcl13 chemokine; major pathological response |
| Journal Title: | Nature Medicine |
| Volume: | 30 |
| Issue: | 9 |
| ISSN: | 1078-8956 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2024-09-01 |
| Start Page: | 2407 |
| End Page: | 2408 |
| Language: | English |
| DOI: | 10.1038/s41591-024-03182-5 |
| PUBMED: | 39117880 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Note -- Source: Scopus |
