Autonomic dysreflexia in patients with cancer and spinal cord injury: A case series Journal Article
| Authors: | Qin, E.; Marshall, G. M.; Ruppert, L. |
| Article Title: | Autonomic dysreflexia in patients with cancer and spinal cord injury: A case series |
| Abstract: | Introduction: Autonomic dysreflexia (AD) is a potentially life-threatening syndrome that can occur in patients with traumatic injury to the spinal cord; however, it has not been well described in patients with non-traumatic spinal cord injury (SCI) from cancer and its treatments. Case presentation: We report four cases of autonomic dysreflexia secondary to primary spinal cord tumors and metastatic disease to the spine, and as sequela to cancer treatment. The clinical characteristics, diagnostic considerations, and therapeutic strategies used to mitigate the symptoms are discussed. Discussion: The case series shows that AD is a rare but important condition to consider among patients with cancer-related SCI. There is a need for close monitoring and early identification of this syndrome in this population. Therapeutic strategies are available to mitigate these symptoms and risks of complications. © The Author(s), under exclusive licence to International Spinal Cord Society 2024. |
| Keywords: | adult; cancer chemotherapy; clinical article; aged; middle aged; range of motion; clinical feature; constipation; case report; cisplatin; doxorubicin; fluorouracil; hypertension; paclitaxel; nuclear magnetic resonance imaging; follow up; neoplasm; metastasis; mastectomy; cyclophosphamide; retrospective study; cancer therapy; patient care; spinal cord; diagnosis; spinal cord compression; spinal cord tumor; patient safety; weakness; headache; motor performance; stereotactic body radiation therapy; metastatic breast cancer; hyperreflexia; gunshot injury; thorax injury; hemangioblastoma; hemangioma; spinal cord injury; spinal cord injuries; axillary lymph node dissection; etiology; spinal cord neoplasms; complication; tonsil cancer; arterial embolization; gait; humans; human; male; female; article; glasgow coma scale; epithelioid hemangioma; autonomic dysreflexia; cord compression myelopathy |
| Journal Title: | Spinal Cord Series and Cases |
| Volume: | 10 |
| ISSN: | 2058-6124 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2024-09-04 |
| Start Page: | 66 |
| Language: | English |
| DOI: | 10.1038/s41394-024-00678-7 |
| PUBMED: | 39231946 |
| PROVIDER: | scopus |
| PMCID: | PMC11375159 |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Lisa Ruppert -- Source: Scopus |
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