Preoperative vascular imaging in lower extremity free flap reconstruction: Comparison between imaging modalities Journal Article


Authors: Ahn, L.; Christensen, J. M.; Fruge, S.; Meulendijks, M. Z.; Hoftiezer, Y. A. J.; Wong, F. K.; Tuano, K. R.; Valerio, I. L.; Eberlin, K. R.
Article Title: Preoperative vascular imaging in lower extremity free flap reconstruction: Comparison between imaging modalities
Abstract: Background: Adequate vascular anatomy and perfusion status are essential for successful lower extremity free tissue transfer. Computed tomography angiography (CTA) is widely available, minimally invasive, and enables visualization of soft tissues and bones. Angiography permits temporal evaluation of flow, identifies potential needs for concurrent endovascular interventions, and enhances visibility in the setting of hardware. Despite widespread availability of these imaging modalities, no standardized algorithm for preoperative imaging prior to lower extremity free flap reconstruction exists. Methods: Current Procedural Terminology (CPT) codes identified patients undergoing free flap reconstruction of the lower extremity over an 18-year period (2002–2020). Electronic medical records were reviewed for patient, treatment, and imaging characteristics, and pre- and post-imaging laboratory values. Outcomes included imaging findings and related complications and surgical outcomes. Results: In total, 405 patients were identified, with 59% (n = 238) undergoing preoperative imaging with angiography, 10% (n = 42) with CTA, 7.2% (n = 29) with both imaging modalities, and 24% (n = 96) with neither performed. Forty percent (122 of 309) of patients who underwent preoperative imaging had less than 3-vessel runoff. Four patients developed contrast-induced nephropathy (CIN) after angiography only and one after having both CTA and angiography. Vessel runoff on CTA and angiography demonstrated moderate correlation. Conclusion: Most patients undergoing lower extremity free tissue transfer underwent preoperative imaging with angiography and/or CTA, 40% of which had less than 3-vessel runoff. Both angiography and CTA had low complication rates, with no statistically significant risk factors identified. Specifically, the incidence of CIN was not found to be significant using either modality. We discuss our institutional algorithm to aid in decision-making for preoperative imaging prior to lower extremity free flap reconstruction. Specifically, we recommend angiography for patients with peripheral vascular disease, internal hardware, or distal defects secondary to trauma. © 2024 Wiley Periodicals LLC.
Keywords: adult; aged; middle aged; limb salvage; retrospective studies; plastic surgery; comparative study; preoperative care; vascularization; retrospective study; arteriography; surgery; free tissue graft; computed tomographic angiography; lower extremity; free flap; free tissue flaps; procedures; ct angiography; microvascular reconstruction; humans; human; male; female; contrast-induced nephropathy; lower limb; computed tomography angiography; plastic surgery procedures
Journal Title: Microsurgery
Volume: 44
Issue: 7
ISSN: 0738-1085
Publisher: Wiley Liss  
Date Published: 2024-10-01
Start Page: e31241
Language: English
DOI: 10.1002/micr.31241
PUBMED: 39301713
PROVIDER: scopus
DOI/URL:
Notes: Article -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Frankie Kin San Wong
    2 Wong