PDX models in theranostic applications: Generation and screening for B cell lymphoma of human origin Review
| Authors: | Shmuel, S.; Monette, S.; Ibrahim, D.; Pereira, P. M. R. |
| Review Title: | PDX models in theranostic applications: Generation and screening for B cell lymphoma of human origin |
| Abstract: | This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma. © The Author(s), under exclusive licence to World Molecular Imaging Society 2024. |
| Keywords: | animal; animals; drug screening; pathology; xenograft model antitumor assays; diagnostic imaging; disease model; b cell lymphoma; lymphoma, b-cell; diagnosis; disease models, animal; personalized medicine; theranostics; ebv; humans; human; precision medicine; pdxs |
| Journal Title: | Molecular Imaging and Biology |
| Volume: | 26 |
| Issue: | 4 |
| ISSN: | 1536-1632 |
| Publisher: | Springer |
| Date Published: | 2024-08-01 |
| Start Page: | 569 |
| End Page: | 576 |
| Language: | English |
| DOI: | 10.1007/s11307-024-01917-x |
| PUBMED: | 38649626 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- MSK Cancer Center Support Grant (P30 CA008748) acknowledged in PDF -- Source: Scopus |
