Molecular imaging in gynecology: Beyond cancer Review


Authors: Sebastiano, J.; Rodriguez, C.; Samuels, Z. V.; Pepin, K.; Zeglis, B. M.
Review Title: Molecular imaging in gynecology: Beyond cancer
Abstract: Gynecological pathologies account for approximately 4.5% of the overall global disease burden. Although cancers of the female reproductive system have understandably been the focus of a great deal of research, benign gynecological conditions—such as endometriosis, polycystic ovary syndrome, and uterine fibroids—have remained stubbornly understudied despite their astonishing ubiquity and grave morbidity. This historical inattention has frequently become manifested in flawed diagnostic and treatment paradigms. Molecular imaging could be instrumental in improving patient care on both fronts. In this Focus on Molecular Imaging review, we will examine recent advances in the use of PET, SPECT, MRI, and fluorescence imaging for the diagnosis and management of benign gynecological conditions, with particular emphasis on recent clinical reports, areas of need, and opportunities for growth. ß 2024 by the Society of Nuclear Medicine and Molecular Imaging.
Keywords: bevacizumab; nuclear magnetic resonance imaging; quality of life; molecular imaging; echography; fluorodeoxyglucose f 18; tracer; gynecology; pet; mri; fluorescence imaging; endometriosis; ovary cyst; spect; ovary polycystic disease; transvaginal echography; leiomyoma; adenomyosis; procedures; adnexa disease; gynecologic disease; indocyanine green; humans; human; female; article; intraoperative imaging; positron emission tomography-computed tomography; malignant neoplasm; parasitic leiomyoma
Journal Title: Journal of Nuclear Medicine
Volume: 65
Issue: 7
ISSN: 0161-5505
Publisher: Society of Nuclear Medicine  
Date Published: 2024-07-01
Start Page: 998
End Page: 1003
Language: English
DOI: 10.2967/jnumed.124.267546
PUBMED: 38871386
PROVIDER: scopus
PMCID: PMC11218728
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Brian Zeglis
    118 Zeglis
  2. Zachary Samuels
    17 Samuels