Authors: | Malhotra, S.; Tadros, A. B. |
Review Title: | New strategies for locally advanced breast cancer: A Review of inflammatory breast cancer and nonresponders |
Abstract: | This review explores the new strategies around the management of locally advanced breast cancer (LABC), particularly for nonresponsive tumors and/or initially unresectable tumors at diagnosis, inclusive of inflammatory breast cancer. Nonresponders to neoadjuvant systemic therapy present a unique clinical challenge. Emerging medical therapeutics as well as considerations for use of radiotherapy and/or surgery in this setting are discussed. Specifically, the use of neoadjuvant radiotherapy for LABC and lymphedema prevention with lymphatic reconstruction following axillary lymph node dissection are reviewed. © 2024 Elsevier Inc. |
Keywords: | cancer surgery; review; systemic therapy; cancer radiotherapy; neoadjuvant therapy; antineoplastic agent; lymph node dissection; lymph node excision; mastectomy; radiotherapy; pathology; breast neoplasms; breast tumor; inoperable cancer; breast surgery; therapy; axillary lymph node dissection; inflammatory breast cancer; procedures; advanced breast cancer; humans; human; female; breast cancer-related lymphedema; neoadjuvant systemic therapy; sacituzumab govitecan; lymphatic reconstruction; inflammatory breast neoplasms |
Journal Title: | Clinical Breast Cancer |
Volume: | 24 |
Issue: | 4 |
ISSN: | 1526-8209 |
Publisher: | Elsevier Inc. |
Date Published: | 2024-06-01 |
Start Page: | 301 |
End Page: | 309 |
Language: | English |
DOI: | 10.1016/j.clbc.2024.01.009 |
PUBMED: | 38431513 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Source: Scopus |