PAK4-targeted PROTACs in clear cell renal cell carcinoma: A two-for-one targeted and immune therapy? Editorial

  


Authors: Bakouny, Z.; Braun, D. A.; Reznik, E.; Hakimi, A. A.
Title: PAK4-targeted PROTACs in clear cell renal cell carcinoma: A two-for-one targeted and immune therapy?
Keywords: nonhuman; note; cd8+ t lymphocyte; cell proliferation; mouse; multiple myeloma; breast cancer; cell infiltration; protein degradation; animal model; tyrosine; renal cell carcinoma; prostate cancer; hypoxia; immune response; immunotherapy; hypoxia inducible factor; clear cell carcinoma; cytotoxic t lymphocyte antigen 4; ubiquitin protein ligase e3; pharmacokinetics; phase 2 clinical trial (topic); epithelial mesenchymal transition; p21 activated kinase 4; immune checkpoint inhibitor
Journal Title: EBioMedicine
Volume: 105
ISSN: 2352-3964
Publisher: Elsevier Inc.  
Date Published: 2024-07-01
Start Page: 105218
Language: English
DOI: 10.1016/j.ebiom.2024.105218
PROVIDER: scopus
PUBMED: 38924842
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85196713438&doi=10.1016%2fj.ebiom.2024.105218&partnerID=40&md5=2319d1f1929ea450a17c6df5a0d0be9c
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Corresponding authors is MSK author: Ziad Bakouny -- Source: Scopus
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MSK Authors
  1. Abraham Ari Hakimi
    323 Hakimi
  2. Eduard Reznik
    103 Reznik
  3. Ziad El Bakouny
    11 El Bakouny
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