Post-mastectomy radiation therapy after breast reconstruction: From historic dogmas to practical expert agreements based on a large literature review of surgical and radiation therapy considerations Review


Authors: Belkacemi, Y.; Moran, M. S.; Ozden, B. C.; Masannat, Y.; Geara, F.; Albashir, M.; To, N. H.; Debbi, K.; El Tamer, M.
Review Title: Post-mastectomy radiation therapy after breast reconstruction: From historic dogmas to practical expert agreements based on a large literature review of surgical and radiation therapy considerations
Abstract: Breast reconstruction (BR) after mastectomy is important to consider for a woman's body image enhancement and psychological well-being. Although post-mastectomy radiation (PMRT) significantly improves the outcome of patients with high-risk breast cancer (BC), PMRT after BR may affect cosmetic outcomes and may compromise the original goal of improving quality of life (QoL). With the lack of practical guidelines, it seems essential to work on a consensus and provide some “expert agreements” to offer patients the best option for PMRT after BR. We report a global “expert agreement” that results from a critical review of the literature on BR and PMRT during the 6th international multidisciplinary breast conference in March 2023. © 2024 Elsevier B.V.
Keywords: adult; major clinical study; review; quality of life; breast cancer; mastectomy; radiotherapy; practice guideline; breast reconstruction; image enhancement; surgery; radiation therapy; disease management; clinical practice guideline; drug therapy; cosmesis; toxicity; prosthesis; body image; flap; diep; human; female; psychological well-being; pmrt
Journal Title: Critical Reviews in Oncology/Hematology
Volume: 200
ISSN: 1040-8428
Publisher: Elsevier Science, Inc.  
Date Published: 2024-08-01
Start Page: 104421
Language: English
DOI: 10.1016/j.critrevonc.2024.104421
PUBMED: 38876160
PROVIDER: scopus
DOI/URL:
Notes: Review -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Mahmoud B. El-Tamer
    105 El-Tamer