Molecular imaging with PET-CT and PET-MRI in pediatric musculoskeletal diseases Review

  


Authors: Guja, K. E.; Behr, G.; Bedmutha, A.; Kuhn, M.; Nadel, H. R.; Pandit-Taskar, N.
Review Title: Molecular imaging with PET-CT and PET-MRI in pediatric musculoskeletal diseases
Abstract: Molecular imaging has emerged as an integral part of oncologic imaging. Given the physiologic changes that precede anatomic changes, molecular imaging can enable early detection of disease and monitoring of response. [18F] Fluorodeoxyglucose (FDG) Positron emission tomography (PET) is the predominant molecular imaging modality used in oncologic assessment and can be performed using PET/CT or PET/MR. In pediatric patients, PET/MRI imaging is generally preferred due to low radiation exposure and PET/MRI is particularly advantageous for imaging musculoskeletal (MSK) diseases, as MRI provides superior characterization of tissue changes as compared to CT. In this article, we provide an overview of the typical role of PET CT/MRI in assessment of some common pediatric malignancies and benign MSK diseases with case examples. We also discuss the relative advantages of PET/MRI compared to PET/CT, and review published data with a primary focus on the use of PET/MR. © 2024
Keywords: osteosarcoma; child; review; nuclear magnetic resonance imaging; magnetic resonance imaging; cancer diagnosis; molecular imaging; diagnostic imaging; childhood cancer; hodgkin disease; ewing sarcoma; bone lesion; neuroblastoma; soft tissue sarcoma; rhabdomyosarcoma; musculoskeletal disease; langerhans cell histiocytosis; comparative effectiveness; musculoskeletal diseases; multimodal imaging; procedures; musculoskeletal tumor; humans; human; chronic osteomyelitis; positron emission tomography-computed tomography; positron emission tomography computed tomography; benign musculoskeletal tumor; chronic recurrent multifocal osteomyelitis
Journal Title: Seminars in Nuclear Medicine
Volume: 54
Issue: 3
ISSN: 0001-2998
Publisher: Elsevier Inc.  
Date Published: 2024-05-01
Start Page: 438
End Page: 455
Language: English
DOI: 10.1053/j.semnuclmed.2024.03.003
PUBMED: 38688770
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191481003&doi=10.1053%2fj.semnuclmed.2024.03.003&partnerID=40&md5=90b42f8cb3aaf041e641368c5c1bcb0a
Notes: Source: Scopus
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MSK Authors
  1. Neeta Pandit-Taskar
    342 Pandit-Taskar
  2. Gerald Gideon Behr
    29 Behr
  3. Akshay Sharad Bedmutha
    8 Bedmutha
  4. Marlena Isabel Kuhn
    2 Kuhn
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