Diffusion model-based single-scan dual-energy cone-beam CT using primary beam splitting Conference Paper


Authors: Peng, J.; Chang, C. W.; Qiu, R. L. J.; Roper, J.; Wang, T.; Patel, P. R.; Yu, D. S.; Tang, X.; Yang, X.
Title: Diffusion model-based single-scan dual-energy cone-beam CT using primary beam splitting
Conference Title: SPIE Medical Imaging 2024: Physics of Medical Imaging
Abstract: Dual-energy cone-beam CT (DECBCT) has great potential for quantitative imaging tasks in CBCT-guided radiation therapy. However, the lack of a practical single-scan solution in data acquisition impedes the practice of CBCT-based adaptive radiotherapy (ART). In this work, we propose an efficient way to achieve DECBCT using the primary beam splitting in a single short scan or half-fan scan. To restore complete dual-energy sinograms sufficient for analytical image reconstruction, the conditional diffusion model is introduced to convert the acquired spectral-mixed sinogram to the complete dual-energy sinograms via a data refinement strategy. The proposed method is compared with the other two diffusion model-based methods and the preliminary results demonstrate the feasibility of the proposed method in quantitative imaging tasks, making it a promising solution to CBCT-based dose calculation and replanning. © 2024 SPIE.
Keywords: radiotherapy; diffusion; computerized tomography; medical imaging; quantitative imaging; image reconstruction; cone-beam ct; data acquisition; dual-energy; model-based opc; sinograms; diffusion model; beam splitting; imaging task; primary beams; single scan
Journal Title Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume: 12925
Conference Dates: 2024 Feb 19-22
Conference Location: San Deigo, CA
ISBN: 1605-7422
Publisher: SPIE  
Date Published: 2024-01-01
Start Page: 129253A
Language: English
DOI: 10.1117/12.3005046
PROVIDER: scopus
DOI/URL:
Notes: Conference paper -- Source: Scopus
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  1. Tonghe Wang
    51 Wang