Practical considerations when choosing chemoembolization versus radioembolization for hepatocellular carcinoma Review
| Authors: | Behzadi, A. H.; Haghani, L.; D'Souza, D. L.; Flanagan, S.; Jones, C. |
| Review Title: | Practical considerations when choosing chemoembolization versus radioembolization for hepatocellular carcinoma |
| Abstract: | Transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) are common liver-directed therapies (LDTs) for unresectable HCC. While both deliver intra-arterial treatment directly to the site of the tumor, they differ in mechanisms of action and side effects. Several studies have compared their side effect profile, time to progression, and overall survival data, but often these lack practical considerations when choosing which treatment modality to use. Many factors can impact operator's choice for treatment, and the choice depends on treatment availability, cost, insurance coverage, operator's comfort level, patient-specific factors, tumor location, tumor biology, and disease stage. This review discusses survival data, time to progression data, as well as more practical patient and tumor characteristics for personalized LDT with TACE or TARE. © 2024 Thieme Medical Publishers, Inc.. All rights reserved. |
| Keywords: | cancer survival; hepatocellular carcinoma; iodinated poppyseed oil; chemoembolization; liver cell carcinoma; liver function; radiation dose; cancer staging; nuclear magnetic resonance imaging; outcome assessment; palliative therapy; risk factor; biopsy; cancer size; interventional radiology; cancer classification; decision making; treatment contraindication; disease exacerbation; economic aspect; race; single photon emission computed tomography; autoimmune hepatitis; yttrium 90; tumor invasion; radioembolization; human; article; liver-directed therapy; lung perfusion; lung shunting; single photon emission computed tomography-computed tomography; liver lobe; right liver lobe; hepatic portal vein; tumor number; t1 weighted imaging; right hepatic artery |
| Journal Title: | Seminars in Interventional Radiology |
| Volume: | 41 |
| Issue: | 1 |
| ISSN: | 0739-9529 |
| Publisher: | Thieme Publishing |
| Date Published: | 2024-02-01 |
| Start Page: | 48 |
| End Page: | 55 |
| Language: | English |
| DOI: | 10.1055/s-0044-1779714 |
| PROVIDER: | scopus |
| PMCID: | PMC10940042 |
| PUBMED: | 38495267 |
| DOI/URL: | |
| Notes: | Source: Scopus |
