Trem-cel, a CRISPR/Cas9 gene-edited allograft lacking CD33, shows rapid primary engraftment with CD33-negative hematopoiesis in patients with high-risk acute myeloid leukemia (AML) and avoids hematopoietic toxicity during gemtuzumab ozogamicin (GO) maintenance post-hematopoietic cell transplant (HCT) Meeting Abstract


Authors: DiPersio, J.; Cooper, B. W.; Suh, H. C.; Koura, D.; Bernard, L.; Shah, N. N.; Walter, R. B.; Perales, M. A.; Mapara, M.; Tamari, R.; Loken, M. R.; Breitschwerdt, K.; Nath, S.; Raffel, G. D.; Koehne, G.
Abstract Title: Trem-cel, a CRISPR/Cas9 gene-edited allograft lacking CD33, shows rapid primary engraftment with CD33-negative hematopoiesis in patients with high-risk acute myeloid leukemia (AML) and avoids hematopoietic toxicity during gemtuzumab ozogamicin (GO) maintenance post-hematopoietic cell transplant (HCT)
Meeting Title: 65th Annual Meeting of the American Society of Hematology (ASH)
Journal Title: Blood
Volume: 142
Issue: Suppl. 1
Meeting Dates: 2023 Dec 9-12
Meeting Location: San Deigo, CA
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2023-11-02
Start Page: 483
Language: English
ACCESSION: WOS:001159306701240
DOI: 10.1182/blood-2023-190037
PROVIDER: wos
Notes: Meeting Abstract -- Source: Wos
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  1. Miguel-Angel Perales
    913 Perales
  2. Roni Tamari
    208 Tamari